AutismKB 2.0

Annotation Detail for USP7


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Basic Information Top
Gene Symbol:USP7 ( HAUSP,TEF1 )
Gene Full Name: ubiquitin specific peptidase 7 (herpes virus-associated)
Band: 16p13.2
Quick LinksEntrez ID:7874; OMIM: 602519; Uniprot ID:UBP7_HUMAN; ENSEMBL ID: ENSG00000187555; HGNC ID: 12630
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
18Phosphoserine.
49Phosphoserine.
54Phosphothreonine.
595N6-acetyllysine.
869N6-acetyllysine.
963Phosphoserine.
1084N6-acetyllysine.
1096N6-acetyllysine.
Location(AA) Modifications Resource
18Phosphoserine.Swiss-Prot 53.0
18PhosphoserinePhospho.ELM 6.0
Location(AA) Modification Resource
18Phosphoserine(CK2)HMM predict
18Phosphoserine(CK2)HMM predict
84Phosphoserine(IKK)HMM predict
127Phosphoserine(CK1)HMM predict
128O-linkedHMM predict
131Phosphoserine(IKK)HMM predict
155Phosphoserine(PKG)HMM predict
213Phosphotyrosine(Jak)HMM predict
347Phosphotyrosine(Syk)HMM predict
347SulfotyrosineHMM predict
348Phosphotyrosine(Syk)HMM predict
525Phosphoserine(CK1)HMM predict
564Phosphotyrosine(Abl)HMM predict
564Phosphotyrosine(INSR)HMM predict
599N-linkedHMM predict
630N-linkedHMM predict
645N-linkedHMM predict
706Phosphotyrosine(INSR)HMM predict
741N-linkedHMM predict
749SulfotyrosineHMM predict
911SulfotyrosineHMM predict
963Phosphoserine(CDC2)HMM predict
1050Phosphotyrosine(INSR)HMM predict
1069N-linkedHMM predict
1091TyrosineHMM predict
1093TyrosineHMM predict
1102AsparagineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_003470
  • Location:chr16 8894850-8964841
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Nanog hESGSE18292 8967360 8967708 348 2693
Oct4 hESGSE21916 8967161 8967844 683 2661
RARA MCF7GSE15244 8968100 8968809 709 3613
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T30-glioblastomaGSE21026 8885738 8886643 905 8660
CTCF G2GSE9613 8887385 8888091 706 7113
P300 T30-glioblastomaGSE21026 8885935 8886629 694 8569
hScc1 BcellGSE12603 8892808 8893417 609 1738
hScc1 CdLSGSE12603 8892808 8893560 752 1667
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP JurkatGSE17954 8911940 8915149 3209 0
CTCF CD4GSE12889 8906685 8906813 128 0
CTCF CD4GSE12889 8937811 8938080 269 0
CTCF CD4SISSRdata 8906685 8906813 128 0
CTCF CD4SISSRdata 8937811 8938080 269 0
CTCF G2GSE9613 8906364 8907312 948 0
CTCF G2GSE9613 8937282 8938080 798 0
CTCF G2GSE9613 8941538 8941864 326 0
CTCF G2GSE9613 8954768 8955576 808 0
CTCF G2GSE9613 8963788 8964299 511 0
ER E2-MCF7GSE14664 8933270 8933304 34 0
FoxA1 MCF7MACSdata 8916337 8916604 267 0
FoxA1 MCF7MACSdata 8939401 8939568 167 0
H3K4me3 colorectalcancer 8962879 8963865 986 0
H3ac HepG2E 8960791 8962526 1735 0
H3ac HepG2E 8962879 8964167 1288 0
NRSF JurkatGSE13047 8932912 8934220 1308 0
NRSF JurkatSISSRdata 8933197 8933704 507 0
NRSF mAbJurkat 8920615 8920984 369 0
NRSF mAbJurkat 8924863 8926074 1211 0
NRSF mAbJurkat 8927895 8928361 466 0
NRSF mAbJurkat 8929368 8932003 2635 0
NRSF mAbJurkat 8932822 8934269 1447 0
NRSF mAbJurkat 8934758 8934941 183 0
NRSF mAbJurkat 8935430 8936534 1104 0
NRSF mAbJurkat 8936866 8938080 1214 0
NRSF-mono JurkatQuESTdata 8933087 8933691 604 0
NRSF-mono JurkatQuESTdata 8933752 8934018 266 0
NRSF pAbJurkat 8932822 8934090 1268 0
NRSF-poly JurkatQuESTdata 8933096 8933921 825 0
Nanog hESGSE18292 8952945 8953363 418 0
Oct1 H2O2-HelaGSE14283 8939654 8939682 28 0
Oct1 HelaGSE14283 8930876 8930938 62 0
Oct1 HelaGSE14283 8933266 8933327 61 0
TFAP2C MCF7GSE21234 8939091 8939570 479 0
VDR GM10855-stimGSE22484 8937154 8938606 1452 0
hScc1 BcellGSE12603 8894872 8895634 762 0
hScc1 BcellGSE12603 8906364 8907037 673 0
hScc1 BcellGSE12603 8937199 8938115 916 0
hScc1 BcellGSE12603 8945880 8946134 254 0
hScc1 BcellGSE12603 8954875 8955370 495 0
hScc1 BcellGSE12603 8963788 8964330 542 0
hScc1 CdLSGSE12603 8906477 8907002 525 0
hScc1 CdLSGSE12603 8937044 8938115 1071 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-125a-3p hsa-mir-125a 19 20542030
hsa-miR-125a-5p hsa-mir-125a 19 20542030
hsa-miR-125b hsa-mir-125b-1 11 20542030
hsa-miR-125b hsa-mir-125b-2 21 20542030
No data
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
9593 EST chr16 8964063 8968294 779 mRNA USP7 chr16 8894850 8964842 Non-exonic Bidirectional (NOB) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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