Annotation Detail for VKORC1

View Evidences	View Variants	View Annotations

Basic Information Top

Gene Symbol:	VKORC1 ( EDTP308,FLJ00289,IMAGE3455200,MGC2694,MST134,MST576,VKCFD2,VKOR )
Gene Full Name:	vitamin K epoxide reductase complex, subunit 1
Band:	16p11.2
Quick Links	Entrez ID:79001; OMIM: 608547; Uniprot ID:VKOR1_HUMAN; ENSEMBL ID: ENSG00000167397; HGNC ID: 23663
Relate to Another Database:	SFARIGene; denovo-db

Pathways, Diseases and Drugs

TF binding site

Post Translation Modification

PTM Sites from Uniprot:0 results
Experimental PTM Sites from dbPTM:0 results
Predicted PTM Sites by profile HMM from dbPTM:4 results

No data

Location(AA)	Modification	Resource
77	N-linked	HMM predict
80	N-linked	HMM predict
96	S-palmitoyl	HMM predict
113	Phosphoserine(IKK)	HMM predict

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

RefSeq ID: NM_024006
Location:chr16 31009676-31013776
strand:-

Upstream the gene:7 results
Downstream the gene:0 results
Inside the gene:16 results

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	CD4	GSE12889	31014761	31014891	130	1050
CTCF	CD4	SISSRdata	31014761	31014891	130	1050
CTCF	G2	GSE9613	31014181	31014850	669	739
TAF	Hela	GSE8489	31014181	31014814	633	721
hScc1	Bcell	GSE12603	31014217	31014850	633	757
hScc1	CdLS	GSE12603	31014434	31014850	416	866
p130	shRbSenescent	GSE19898	31014375	31014487	112	655

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
ETS1	Jurkat	GSE17954	31013243	31014191	948	0
H3ac	HepG2	E	31011910	31012486	576	0
H3ac	HepG2	E	31012841	31013400	559	0
PHF8	HeLa	GSE20725	31012752	31014040	1288	0
Rb	Growing	GSE19898	31013652	31013795	143	0
Rb	Senescent	GSE19898	31013145	31013850	705	0
Rb	shRbSenescence	GSE19898	31012895	31013133	238	0
TAF	Hela	GSE8489	31012841	31013057	216	0
TFAP2C	MCF7	GSE21234	31013218	31013909	691	0
hScc1	Bcell	GSE12603	31012933	31013574	641	0
p130	Quiescent	GSE19898	31013522	31013929	407	0
p130	Senescent	GSE19898	31012904	31013089	185	0
p130	Senescent	GSE19898	31013601	31013934	333	0
p130	shRbQuiescent	GSE19898	31012887	31013392	505	0
p130	shRbQuiescent	GSE19898	31013412	31014008	596	0
p130	shRbSenescent	GSE19898	31013164	31013896	732	0

Validated miRNA targets

miR Walk:6 results
Tarbase V5.0:0 results

Micro RNA Name	Stem Loop Name	The chromosome that miRNA located	Publication
hsa-miR-133a	hsa-mir-133a-1	18	20415550
hsa-miR-133a	hsa-mir-133a-2	20	20415550
hsa-miR-133b	hsa-mir-133b	6	20415550
hsa-miR-137	hsa-mir-137	1	20415550
hsa-miR-22	hsa-mir-22	17	20415550
hsa-miR-22*	hsa-mir-22	17	20415550

Cis-Nats regulation

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

Studies: 1,036
Genes: 1,379
CNVs/SVs: 5,420
SNVs/Indels: 11,669
de novo Mutations: 5,669
Mosaics: 789
Linkage Regions: 172

Paper Collected: 6/30/2018

Last Update: 8/26/2018

Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved