AutismKB 2.0

Annotation Detail for DERL1


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Basic Information Top
Gene Symbol:DERL1 ( DER-1,DER1,FLJ13784,FLJ42092,MGC3067,PRO2577 )
Gene Full Name: Der1-like domain family, member 1
Band: 8q24.13
Quick LinksEntrez ID:79139; OMIM: 608813; Uniprot ID:DERL1_HUMAN; ENSEMBL ID: ENSG00000136986; HGNC ID: 28454
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
202Phosphothreonine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
35Phosphoserine(MAPK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_024295
  • Location:chr8 124094768-124123721
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FOXA1 MCF7GSE15244 124134638 124134821 183 11008
Nanog ESGSE20650 124133860 124134072 212 10245
Rb QuiescentGSE19898 124123629 124123871 242 29
p130 shRbQuiescentGSE19898 124123231 124124257 1026 23
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FOXA1 MCF7GSE15244 124076212 124076549 337 18388
FOXA1 MCF7GSE15244 124090349 124090823 474 4183
RARA MCF7GSE15244 124076179 124076847 668 18256
RARG MCF7GSE15244 124076212 124076549 337 18388
RARG MCF7GSE15244 124077283 124077646 363 17304
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 124103896 124104263 367 0
CTCF CD4GSE12889 124119783 124119992 209 0
CTCF CD4SISSRdata 124103896 124104263 367 0
CTCF CD4SISSRdata 124119783 124119992 209 0
ETS1 JurkatGSE17954 124122771 124124155 1384 0
FOXA1 MCF7GSE15244 124119710 124120627 917 0
FOXA1 MCF7GSE15244 124123107 124123946 839 0
H3K4me2 HCT116GSE10453 124121670 124123180 1510 0
H3K4me3 colorectalcancer 124121670 124123837 2167 0
H3ac HepG2E 124121740 124122172 432 0
H3ac HepG2E 124122493 124123213 720 0
LIN9 SGSE7516 124123144 124123800 656 0
Oct1 H2O2-HelaGSE14283 124098958 124098989 31 0
Oct1 HelaGSE14283 124098958 124098989 31 0
PHF8 HeLaGSE20725 124123010 124124285 1275 0
RARA MCF7GSE15244 124099853 124100932 1079 0
RARA MCF7GSE15244 124119020 124120243 1223 0
USF1 HepG2E 124122457 124123265 808 0
hScc1 BcellGSE12603 124103759 124104244 485 0
hScc1 BcellGSE12603 124123265 124123837 572 0
hScc1 CdLSGSE12603 124103617 124104283 666 0
p130 QuiescentGSE19898 124123044 124123195 151 0
p130 SenescentGSE19898 124123004 124124043 1039 0
p130 shRbSenescentGSE19898 124122980 124123964 984 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-let-7a hsa-let-7a-1 9 19342589
hsa-let-7a hsa-let-7a-2 11 19342589
hsa-let-7a hsa-let-7a-3 22 19342589
hsa-let-7a* hsa-let-7a-1 9 19342589
hsa-let-7a* hsa-let-7a-3 22 19342589
hsa-let-7b hsa-let-7b 22 19342589
hsa-let-7b* hsa-let-7b 22 19342589
hsa-let-7c hsa-let-7c 21 19342589
hsa-let-7c* hsa-let-7c 21 19342589
hsa-let-7d hsa-let-7d 9 19342589
hsa-let-7d* hsa-let-7d 9 19342589
hsa-let-7e hsa-let-7e 19 19342589
hsa-let-7e* hsa-let-7e 19 19342589
hsa-let-7f hsa-let-7f-1 9 19342589
hsa-let-7f hsa-let-7f-2 X 19342589
hsa-let-7f-1* hsa-let-7f-1 9 19342589
hsa-let-7f-2* hsa-let-7f-2 X 19342589
hsa-let-7g hsa-let-7g 3 19342589
hsa-let-7g* hsa-let-7g 3 19342589
hsa-let-7i hsa-let-7i 12 19342589
hsa-let-7i* hsa-let-7i 12 19342589
hsa-miR-21 hsa-mir-21 17 19342589
hsa-miR-21* hsa-mir-21 17 19342589
No data
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
25908 EST chr8 124083980 124112172 112 mRNA DERL1 chr8 124094768 124123722Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018