AutismKB 2.0

Annotation Detail for IRX3


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Basic Information Top
Gene Symbol:IRX3 ( FLJ99187,IRX-1,IRXB1 )
Gene Full Name: iroquois homeobox 3
Band: 16q12.2
Quick LinksEntrez ID:79191; OMIM: 612985; Uniprot ID:IRX3_HUMAN; ENSEMBL ID: ENSG00000177508; HGNC ID: 14360
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
26O-linkedHMM predict
33MethylarginineHMM predict
44N-linkedHMM predict
98Phosphoserine(CDC2)HMM predict
120SulfotyrosineHMM predict
133N-linkedHMM predict
156Phosphothreonine(PKC)HMM predict
206Phosphotyrosine(INSR)HMM predict
206SulfotyrosineHMM predict
206Phosphotyrosine(Abl)HMM predict
208Phosphoserine(CK2)HMM predict
264Phosphothreonine(PKC)HMM predict
269Phosphoserine(CK1)HMM predict
291Phosphoserine(CK2)HMM predict
291Phosphoserine(CK1)HMM predict
293Phosphoserine(CK2)HMM predict
296Phosphoserine(CK1)HMM predict
296PhosphoserineHMM predict
309O-linkedHMM predict
321O-linkedHMM predict
321Phosphoserine(MAPK)HMM predict
323O-linkedHMM predict
330O-linkedHMM predict
357O-linkedHMM predict
358Phosphoserine(CDC2)HMM predict
365Phosphoserine(CDC2)HMM predict
372O-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_024336
  • Location:chr16 52874712-52877878
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3K27me3 colorectalcancer 52879594 52880374 780 2106
H3K27me3 colorectalcancer 52881038 52881688 650 3485
H3K27me3 colorectalcancer 52882073 52883492 1419 4904
Oct1 HelaGSE14283 52891381 52891408 27 13516
hScc1 BcellGSE12603 52877659 52878571 912 237
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3ac HepG2E 52868918 52870047 1129 5230
TAF HelaGSE8489 52873526 52873923 397 988
USF1 HepG2E 52857337 52857831 494 17129
USF1 HepG2E 52859488 52860675 1187 14631
USF1 HepG2E 52861635 52862835 1200 12478
USF2 HepG2E 52859850 52860642 792 14467
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 52876002 52877226 1224 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018