AutismKB 2.0

Annotation Detail for KREMEN2


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Basic Information Top
Gene Symbol:KREMEN2 ( KRM2,MGC10791,MGC16709 )
Gene Full Name: kringle containing transmembrane protein 2
Band: 16p13.3
Quick LinksEntrez ID:79412; OMIM: 609899; Uniprot ID:KREM2_HUMAN; ENSEMBL ID: ENSG00000131650; HGNC ID: 18797
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
49N-linked (GlcNAc...) (Potential).
222N-linked (GlcNAc...) (Potential).
244N-linked (GlcNAc...) (Potential).
351N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
49N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
222N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
244N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
351N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
30Phosphoserine(MAPK)HMM predict
49N-linkedHMM predict
72O-linkedHMM predict
138O-linkedHMM predict
138O-linkedHMM predict
141O-linkedHMM predict
143O-linkedHMM predict
144O-linkedHMM predict
222N-linkedHMM predict
239SulfotyrosineHMM predict
313MethylarginineHMM predict
339O-linkedHMM predict
342Phosphothreonine(CDC2)HMM predict
351N-linkedHMM predict
355O-linkedHMM predict
410MethylarginineHMM predict
415Phosphoserine(PKA)HMM predict
431Phosphoserine(ATM)HMM predict
451Phosphoserine(ATM)HMM predict
451Phosphoserine(CK1)HMM predict
453Phosphoserine(CK1)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_024507
  • Location:chr16 2954217-2958380
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 2951759 2952044 285 2316
CTCF CD4SISSRdata 2951759 2952044 285 2316
CTCF G2GSE9613 2951568 2953442 1874 1713
NFkBII GM10847GSE19485 2952940 2954106 1166 695
NFkBII GM12892GSE19485 2952795 2954540 1745 550
hScc1 BcellGSE12603 2951642 2952122 480 2336
hScc1 CdLSGSE12603 2951673 2952122 449 2320
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
NRSF JurkatGSE13047 2957939 2959593 1654 386
TFAP2C MCF7GSE21234 2958603 2959194 591 518
p130 shRbSenescentGSE19898 2958575 2959367 792 591
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 2954182 2955221 1039 0
H3K27me3 colorectalcancer 2955801 2956056 255 0
hScc1 BcellGSE12603 2956859 2957500 641 0
hScc1 CdLSGSE12603 2956813 2957427 614 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018