AutismKB 2.0

Annotation Detail for WDR25


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Basic Information Top
Gene Symbol:WDR25 ( MGC4645 )
Gene Full Name: WD repeat domain 25
Band: 14q32.32
Quick LinksEntrez ID:79446; OMIM: NA; Uniprot ID:WDR25_HUMAN; ENSEMBL ID: ENSG00000176473; HGNC ID: 21064
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
459Phosphotyrosine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
7Phosphoserine(PKA)HMM predict
20Phosphoserine(CK2)HMM predict
20Phosphoserine(CK1)HMM predict
20Phosphoserine(IKK)HMM predict
31N-linkedHMM predict
90Phosphoserine(IKK)HMM predict
160N-linkedHMM predict
177Phosphothreonine(MAPK)HMM predict
177Phosphothreonine(CDK)HMM predict
338Phosphothreonine(PKC)HMM predict
402Phosphoserine(PKA)HMM predict
537GlycineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_024515
  • Location:chr14 99912702-100066390
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ETS1 JurkatGSE17954 99912003 99913199 1196 102
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
hScc1 BcellGSE12603 100067880 100068290 410 1695
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 100060944 100061198 254 0
CTCF CD4GSE12889 99913920 99914237 317 0
CTCF CD4GSE12889 99919841 99920065 224 0
CTCF CD4GSE12889 99976375 99976547 172 0
CTCF CD4SISSRdata 100060944 100061198 254 0
CTCF CD4SISSRdata 99913920 99914237 317 0
CTCF CD4SISSRdata 99919841 99920065 224 0
CTCF CD4SISSRdata 99976375 99976547 172 0
CTCF JurkatGSE12889 99919736 99920051 315 0
CTCF G2GSE9613 100003345 100003556 211 0
CTCF G2GSE9613 100005062 100005328 266 0
CTCF G2GSE9613 100059396 100059548 152 0
CTCF G2GSE9613 100065701 100065918 217 0
CTCF G2GSE9613 99913705 99914157 452 0
CTCF G2GSE9613 99919631 99920485 854 0
CTCF G2GSE9613 99921139 99921385 246 0
CTCF G2GSE9613 99953784 99953995 211 0
CTCF G2GSE9613 99960871 99961367 496 0
CTCF G2GSE9613 99976356 99976821 465 0
Fos K562GSE19551 99944401 99945041 640 0
Fos K562GSE19551 99982579 99983119 540 0
GABP HelaGSE8489 99912842 99913189 347 0
GABP k562GSE8489 99912695 99913189 494 0
GABP k562GSE8489 99913705 99914195 490 0
H3ac HepG2E 99912731 99913357 626 0
Myc K562GSE19551 99983277 99983647 370 0
NRSF JurkatGSE13047 100022098 100025467 3369 0
NRSF mAbJurkat 100018674 100018969 295 0
NRSF mAbJurkat 100019330 100023392 4062 0
NRSF mAbJurkat 100023973 100024478 505 0
NRSF mAbJurkat 100024825 100027058 2233 0
NRSF-mono JurkatQuESTdata 100022006 100023449 1443 0
NRSF-poly JurkatQuESTdata 100022104 100023340 1236 0
Nanog hESGSE18292 100002010 100002697 687 0
Oct1 H2O2-HelaGSE14283 100038454 100038487 33 0
Oct1 HelaGSE14283 99990296 99990323 27 0
P300 T30-glioblastomaGSE21026 100012067 100013184 1117 0
P300 T30-glioblastomaGSE21026 99944399 99945051 652 0
RARA MCF7GSE15244 100007759 100008275 516 0
RARA MCF7GSE15244 100012346 100013296 950 0
RARG MCF7GSE15244 99913705 99914120 415 0
RARG MCF7GSE15244 99959471 99959850 379 0
RARG MCF7GSE15244 99975334 99975699 365 0
RARG MCF7GSE15244 99976783 99977167 384 0
Sox2 hESGSE18292 99945905 99946337 432 0
TFAP2C MCF7GSE21234 100007794 100008577 783 0
TFAP2C MCF7GSE21234 100022410 100022953 543 0
hScc1 BcellGSE12603 99913705 99914231 526 0
hScc1 BcellGSE12603 99919631 99920303 672 0
hScc1 BcellGSE12603 99975139 99975531 392 0
hScc1 BcellGSE12603 99976216 99976682 466 0
hScc1 BcellGSE12603 99999908 100000213 305 0
hScc1 CdLSGSE12603 99913705 99914231 526 0
hScc1 CdLSGSE12603 99919631 99920522 891 0
p130 shRbQuiescentGSE19898 99945096 99945602 506 0
p63 keratinocytesGSE17611 99933815 99934805 990 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
8371 mRNA MGC4645 chr14 99912702 100066393 92 mRNA WARS chr14 99870802 99912895Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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