AutismKB 2.0

Annotation Detail for CDC73


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:CDC73 ( C1orf28,FLJ23316,HPTJT,HRPT2,HYX )
Gene Full Name: cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
Band: 1q31.2
Quick LinksEntrez ID:79577; OMIM: 607393; Uniprot ID:CDC73_HUMAN; ENSEMBL ID: ENSG00000134371; HGNC ID: 16783
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
2N-acetylalanine.
139Nuclear localization signal.
174Phosphoserine.
178Phosphoserine.
212Phosphoserine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
6Phosphoserine(CK1)HMM predict
97Phosphotyrosine(INSR)HMM predict
174Phosphoserine(CAMK2)HMM predict
178Phosphoserine(CK1)HMM predict
196Phosphothreonine(PKA)HMM predict
235Phosphothreonine(PKA)HMM predict
293SulfotyrosineHMM predict
334Phosphothreonine(PKA)HMM predict
334Phosphothreonine(MAPK)HMM predict
345O-linkedHMM predict
345O-linkedHMM predict
345Phosphoserine(IKK)HMM predict
370O-linkedHMM predict
401N-linkedHMM predict
514PhenylalanineHMM predict
517PhenylalanineHMM predict
531PhenylalanineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_024529
  • Location:chr1 191357783-191487678
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 191357515 191357978 463 37
CTCF CD4SISSRdata 191357515 191357978 463 37
ETS1 JurkatGSE17954 191357173 191358255 1082 70
PHF8 HeLaGSE20725 191356915 191358461 1546 96
TAF k562GSE8489 191356387 191357111 724 1035
VDR GM10861-UnstimGSE22484 191356804 191358685 1881 39
hScc1 BcellGSE12603 191357301 191357985 684 141
p130 SenescentGSE19898 191351189 191351511 322 6434
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Oct1 HelaGSE14283 191496735 191496788 53 9083
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 191379165 191379309 144 0
CTCF CD4SISSRdata 191379165 191379309 144 0
CTCF G2GSE9613 191357516 191358263 747 0
ER E2-MCF7GSE14664 191364343 191364438 95 0
ER E2-MCF7GSE14664 191428205 191428267 62 0
ER Fulvestrant-MCF7GSE14664 191428274 191428316 42 0
H3K4me3 colorectalcancer 191358056 191358924 868 0
H3ac HepG2E 191358056 191358924 868 0
Nanog hESGSE18292 191457327 191457980 653 0
Oct1 HelaGSE14283 191379020 191379052 32 0
Oct1 HelaGSE14283 191393140 191393173 33 0
Oct1 HelaGSE14283 191448859 191448889 30 0
Oct1 HelaGSE14283 191477088 191477118 30 0
TAF HelaGSE8489 191358130 191358924 794 0
TAF k562GSE8489 191358056 191358924 868 0
TAF k562GSE8489 191359332 191360534 1202 0
p130 QuiescentGSE19898 191357933 191358065 132 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-139-3p hsa-mir-139 11 19926710
hsa-miR-139-5p hsa-mir-139 11 19926710
hsa-miR-222 hsa-mir-222 X 19926710
hsa-miR-222* hsa-mir-222 X 19926710
hsa-miR-296-3p hsa-mir-296 20 19926710
hsa-miR-296-5p hsa-mir-296 20 19926710
hsa-miR-503 hsa-mir-503 X 19926710
No data
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
2092 mRNA HRPT2 chr1 189822817 189952713 240 EST chr1 189952217 189952457Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved