Annotation Detail for PARP8

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Basic Information Top

Gene Symbol:	PARP8 ( FLJ21308,MGC42864,pART16 )
Gene Full Name:	poly (ADP-ribose) polymerase family, member 8
Band:	5q11.1
Quick Links	Entrez ID:79668; OMIM: NA; Uniprot ID:PARP8_HUMAN; ENSEMBL ID: ENSG00000151883; HGNC ID: 26124
Relate to Another Database:	SFARIGene; denovo-db

Post Translation Modification

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
ER	Fulvestrant-MCF7	GSE14664	49997662	49997694	32	892
H3K4me2	HCT116	GSE10453	49997243	49997775	532	1061
H3K4me3	colorectal	cancer	49997171	49998082	911	943
Oct1	Hela	GSE14283	49978744	49978774	30	19811
RARA	MCF7	GSE15244	49996959	49997730	771	1225
hScc1	Bcell	GSE12603	49997208	49997775	567	1078

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length
CTCF	CD4	GSE12889	50082574	50082978	404
CTCF	CD4	SISSRdata	50082574	50082978	404
CTCF	G2	GSE9613	49998162	49999540	1378
CTCF	G2	GSE9613	50082697	50083001	304
ER	E2-MCF7	GSE14664	50060705	50060738	33
ER	E2-MCF7	GSE14664	50163949	50163986	37
FOXA1	MCF7	GSE15244	50014438	50014995	557
H3K4me2	HCT116	GSE10453	49999576	50000349	773
H3K4me3	colorectal	cancer	49999656	50000546	890
H3ac	HepG2	E	49999540	50000436	896
KLF4	hES	GSE17917	50046287	50046523	236
NFkBII	GM10847	GSE19485	49997436	50000202	2766
NFkBII	GM12878	GSE19485	49998310	50000955	2645
NFkBII	GM12892	GSE19485	49997305	50000372	3067
NFkBII	GM15510	GSE19485	49997821	50000396	2575
NFkBII	GM18526	GSE19485	49997363	50000201	2838
Nanog	hES	GSE18292	50010294	50010505	211
Nanog	hES	GSE18292	50082763	50082932	169
Oct1	H2O2-Hela	GSE14283	50081000	50081028	28
Oct1	H2O2-Hela	GSE14283	50082406	50082436	30
Oct1	Hela	GSE14283	50082405	50082445	40
Oct1	Hela	GSE14283	50086270	50086304	34
Oct1	Hela	GSE14283	50116269	50116324	55
Oct1	Hela	GSE14283	50163949	50163983	34
Stat6	IL-4-hr4	GSE17850	50021223	50021686	463
TAF	Hela	GSE8489	49999437	50000610	1173
TFAP2C	MCF7	GSE21234	50126393	50126784	391
hScc1	Bcell	GSE12603	49998538	50000031	1493
hScc1	Bcell	GSE12603	50082463	50083072	609
hScc1	CdLS	GSE12603	49997313	50000110	2797
hScc1	CdLS	GSE12603	50082512	50083138	626
p130	Quiescent	GSE19898	49998860	49999094	234
p130	Senescent	GSE19898	49998816	49999103	287

Validated miRNA targets

Micro RNA Name	Stem Loop Name	The chromosome that miRNA located	Publication
hsa-let-7b	hsa-let-7b	22	15131085
hsa-let-7b*	hsa-let-7b	22	15131085
hsa-let-7e	hsa-let-7e	19	15131085
hsa-let-7e*	hsa-let-7e	19	15131085
hsa-miR-103	hsa-mir-103-2	20	15131085
hsa-miR-103	hsa-mir-103-1	5	15131085
hsa-miR-141	hsa-mir-141	12	15131085
hsa-miR-141*	hsa-mir-141	12	15131085
hsa-miR-145	hsa-mir-145	5	15131085
hsa-miR-145*	hsa-mir-145	5	15131085
hsa-miR-15a	hsa-mir-15a	13	15131085
hsa-miR-15a*	hsa-mir-15a	13	15131085
hsa-miR-15b	hsa-mir-15b	3	15131085
hsa-miR-15b*	hsa-mir-15b	3	15131085
hsa-miR-16	hsa-mir-16-1	13	15131085
hsa-miR-16	hsa-mir-16-2	3	15131085
hsa-miR-199b-3p	hsa-mir-199b	9	15131085
hsa-miR-199b-5p	hsa-mir-199b	9	15131085
hsa-miR-23a	hsa-mir-23a	19	15131085
hsa-miR-23a*	hsa-mir-23a	19	15131085
hsa-miR-24	hsa-mir-24-1	9	15131085
hsa-miR-24	hsa-mir-24-2	19	15131085

Cis-Nats regulation

Cluster ID	Plue Type	Plus Gene Name	Plus Chromosome	Plus Start	Plus End	Overlap Length	Minus Type	Minus Gene Name	Minus Chromosome	Minus Star	Minus End	Type
20929	mRNA	PARP8	chr5	49998569	50173933	102	EST		chr5	49998675	49998815	Sense/Antisense (SA) pairs

Simple Query:

Paper Collected: 6/30/2018

Last Update: 8/26/2018