Annotation Detail for IPO4
Basic Information Top
| Gene Symbol: | IPO4 ( FLJ23338,Imp4,MGC131665 ) |
|---|---|
| Gene Full Name: | importin 4 |
| Band: | 14q12 |
| Quick Links | Entrez ID:79711; OMIM: NA; Uniprot ID:IPO4_HUMAN; ENSEMBL ID: ENSG00000196497; HGNC ID: 19426 |
| Relate to Another Database: | SFARIGene; denovo-db |
| Location(AA) | Modification | |
|---|---|---|
| 1 | N-acetylmethionine. | |
| 86 | Phosphothreonine. | |
| Location(AA) | Modifications | Resource |
|---|---|---|
| 1 | N-acetylmethionine. | Swiss-Prot 53.0 |
| 86 | Phosphothreonine. | Swiss-Prot 53.0 |
| Location(AA) | Modification | Resource |
|---|---|---|
| 25 | Phosphothreonine(PKA) | HMM predict |
| 61 | Phosphothreonine(PKC) | HMM predict |
| 129 | Phosphoserine(ATM) | HMM predict |
| 129 | Phosphoserine(IKK) | HMM predict |
| 132 | Phosphoserine(MAPK) | HMM predict |
| 165 | N-linked | HMM predict |
| 186 | O-linked | HMM predict |
| 190 | Phosphotyrosine(Jak) | HMM predict |
| 269 | S-palmitoyl | HMM predict |
| 270 | S-palmitoyl | HMM predict |
| 315 | Phosphoserine(CK1) | HMM predict |
| 315 | Phosphoserine(CK2) | HMM predict |
| 443 | Phosphotyrosine(Jak) | HMM predict |
| 490 | N-linked | HMM predict |
| 493 | Phosphoserine | HMM predict |
| 493 | Phosphoserine(CDK) | HMM predict |
| 493 | Phosphoserine(MAPK) | HMM predict |
| 493 | Phosphoserine(CDC2) | HMM predict |
| 639 | Phosphoserine(CK2) | HMM predict |
| 658 | Phosphoserine(CK1) | HMM predict |
| 661 | Phosphoserine(CK1) | HMM predict |
| 734 | Phosphoserine(IKK) | HMM predict |
| 737 | Phosphoserine(CK1) | HMM predict |
| 813 | Phosphothreonine(CK2) | HMM predict |
| 827 | Phosphotyrosine(Syk) | HMM predict |
| 827 | Sulfotyrosine | HMM predict |
| 972 | Phosphoserine(CDC2) | HMM predict |
| 972 | Phosphoserine(CDK) | HMM predict |
| 1000 | Phosphothreonine(PKC) | HMM predict |
- RefSeq ID: NM_024658
- Location:chr14 23719265-23727963
- strand:-
| No data |
| No data |
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| CTCF | G2 | GSE9613 | 23720442 | 23721053 | 611 | 0 |
| CTCF | G2 | GSE9613 | 23723783 | 23724103 | 320 | 0 |
| CTCF | G2 | GSE9613 | 23727252 | 23727983 | 731 | 0 |
| ETS1 | Jurkat | GSE17954 | 23727260 | 23728544 | 1284 | 0 |
| H3ac | HepG2 | E | 23726439 | 23727815 | 1376 | 0 |
| Myc | K562 | GSE19551 | 23727216 | 23728203 | 987 | 0 |
| Myc | hES | GSE17917 | 23727710 | 23728099 | 389 | 0 |
| P300 | T30-glioblastoma | GSE21026 | 23727189 | 23728213 | 1024 | 0 |
| PHF8 | HeLa | GSE20725 | 23727063 | 23728279 | 1216 | 0 |
| VDR | GM10861-Unstim | GSE22484 | 23726685 | 23728761 | 2076 | 0 |
| VDR | GM10861-stim | GSE22484 | 23726665 | 23728635 | 1970 | 0 |
| hScc1 | Bcell | GSE12603 | 23720615 | 23721089 | 474 | 0 |
| hScc1 | Bcell | GSE12603 | 23723744 | 23724103 | 359 | 0 |
| hScc1 | Bcell | GSE12603 | 23727177 | 23727949 | 772 | 0 |
| Micro RNA Name | Stem Loop Name | The chromosome that miRNA located | Publication |
|---|---|---|---|
| hsa-let-7b | hsa-let-7b | 22 | 18668040 |
| hsa-let-7b | hsa-let-7b | 22 | 18668040 |
| hsa-let-7b* | hsa-let-7b | 22 | 18668040 |
| hsa-let-7b* | hsa-let-7b | 22 | 18668040 |
| hsa-miR-1 | hsa-mir-1-2 | 18 | 18668040 |
| hsa-miR-1 | hsa-mir-1-1 | 20 | 18668040 |
| hsa-miR-1 | hsa-mir-1-2 | 18 | 18668040 |
| hsa-miR-1 | hsa-mir-1-1 | 20 | 18668040 |
| hsa-miR-155 | hsa-mir-155 | 21 | 18668040 |
| hsa-miR-155 | hsa-mir-155 | 21 | 18668040 |
| hsa-miR-155* | hsa-mir-155 | 21 | 18668040 |
| hsa-miR-155* | hsa-mir-155 | 21 | 18668040 |
| hsa-miR-16 | hsa-mir-16-1 | 13 | 18668040 |
| hsa-miR-16 | hsa-mir-16-2 | 3 | 18668040 |
| hsa-miR-16 | hsa-mir-16-1 | 13 | 18668040 |
| hsa-miR-16 | hsa-mir-16-2 | 3 | 18668040 |
| hsa-miR-30a | hsa-mir-30a | 6 | 18668040 |
| hsa-miR-30a | hsa-mir-30a | 6 | 18668040 |
| hsa-miR-30a* | hsa-mir-30a | 6 | 18668040 |
| hsa-miR-30a* | hsa-mir-30a | 6 | 18668040 |
| hsa-miR-30b | hsa-mir-30b | 8 | 18668040 |
| hsa-miR-30b | hsa-mir-30b | 8 | 18668040 |
| hsa-miR-30b* | hsa-mir-30b | 8 | 18668040 |
| hsa-miR-30b* | hsa-mir-30b | 8 | 18668040 |
| hsa-miR-30c | hsa-mir-30c-2 | 6 | 18668040 |
| hsa-miR-30c | hsa-mir-30c-1 | 1 | 18668040 |
| hsa-miR-30c | hsa-mir-30c-2 | 6 | 18668040 |
| hsa-miR-30c | hsa-mir-30c-1 | 1 | 18668040 |
| hsa-miR-30c-1* | hsa-mir-30c-1 | 1 | 18668040 |
| hsa-miR-30c-1* | hsa-mir-30c-1 | 1 | 18668040 |
| hsa-miR-30c-2* | hsa-mir-30c-2 | 6 | 18668040 |
| hsa-miR-30c-2* | hsa-mir-30c-2 | 6 | 18668040 |
| hsa-miR-30d | hsa-mir-30d | 8 | 18668040 |
| hsa-miR-30d | hsa-mir-30d | 8 | 18668040 |
| hsa-miR-30d* | hsa-mir-30d | 8 | 18668040 |
| hsa-miR-30d* | hsa-mir-30d | 8 | 18668040 |
| hsa-miR-30e | hsa-mir-30e | 1 | 18668040 |
| hsa-miR-30e | hsa-mir-30e | 1 | 18668040 |
| hsa-miR-30e* | hsa-mir-30e | 1 | 18668040 |
| hsa-miR-30e* | hsa-mir-30e | 1 | 18668040 |
| ID in Tarbase | Data Type | Support Type | miRNA | Gene | Direct Support | Publication |
|---|---|---|---|---|---|---|
| 867 | Unknown | pSILAC | let-7b | IPO4 | down 50-25% | 18668040 |
| 1060 | Unknown | pSILAC | miR-16 | IPO4 | down 50-25% | 18668040 |
| Ensembl | Protein Type | Differentially expressed in | Pathology or Event | Mis Regulation | Gene Expression | Tumour Involvement |
| ENSG00000196497 | n_a | n_a | n_a | "epithelium, lymphocyte, muscle cell" | "benign tumour, malignant tumour, carcinoma, sarcoma" | |
| ENSG00000196497 | n_a | n_a | n_a | "epithelium, lymphocyte, muscle cell" | "benign tumour, malignant tumour, carcinoma, sarcoma" |
| Cluster ID | Plue Type | Plus Gene Name | Plus Chromosome | Plus Start | Plus End | Overlap Length | Minus Type | Minus Gene Name | Minus Chromosome | Minus Star | Minus End | Type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 7709 | mRNA | REC8L1 | chr14 | 23711073 | 23719302 | 39 | mRNA | IPO4 | chr14 | 23719263 | 23722912 | Sense/Antisense (SA) pairs |