AutismKB 2.0

Annotation Detail for WDR59


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:WDR59 ( FLJ12270,MGC11230 )
Gene Full Name: WD repeat domain 59
Band: 16q23.1
Quick LinksEntrez ID:79726; OMIM: NA; Uniprot ID:WDR59_HUMAN; ENSEMBL ID: ENSG00000103091; HGNC ID: 25706
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
564Phosphoserine.
821Phosphoserine.
822Phosphoserine.
830Phosphoserine.
Location(AA) Modifications Resource
821Phosphoserine (By similarity).Swiss-Prot 53.0
Location(AA) Modification Resource
55Phosphoserine(PKG)HMM predict
131SulfotyrosineHMM predict
142Phosphothreonine(PKA)HMM predict
181Phosphoserine(PKG)HMM predict
211Phosphoserine(ATM)HMM predict
243Phosphothreonine(CDK)HMM predict
449N-linkedHMM predict
456O-linkedHMM predict
478Phosphoserine(IKK)HMM predict
489Phosphoserine(IKK)HMM predict
511Phosphoserine(IKK)HMM predict
513Phosphothreonine(CDK)HMM predict
523O-linkedHMM predict
564O-linkedHMM predict
564Phosphoserine(IKK)HMM predict
564Phosphoserine(CDC2)HMM predict
566O-linkedHMM predict
569Phosphothreonine(CDK)HMM predict
569Phosphothreonine(MAPK)HMM predict
603Phosphoserine(CDC2)HMM predict
605Phosphothreonine(PKC)HMM predict
607Phosphoserine(CK1)HMM predict
629Phosphoserine(PKG)HMM predict
634Phosphoserine(CK1)HMM predict
634Phosphoserine(CK2)HMM predict
784Phosphoserine(IKK)HMM predict
790Phosphoserine(IKK)HMM predict
790O-linkedHMM predict
793Phosphoserine(IKK)HMM predict
815Phosphoserine(CK1)HMM predict
833Phosphotyrosine(INSR)HMM predict
907Phosphoserine(CK1)HMM predict
963GlycineHMM predict
964CysteineHMM predict
968S-farnesylHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_030581
  • Location:chr16 73464971-73576517
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 73576246 73576835 589 23
Fos K562GSE19551 73576414 73577017 603 198
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 73454140 73454440 300 10682
CTCF CD4SISSRdata 73454140 73454440 300 10682
CTCF G2GSE9613 73454085 73454464 379 10697
Nanog hESGSE18292 73454216 73454479 263 10624
Oct4 hESGSE21916 73462893 73463389 496 1831
hScc1 BcellGSE12603 73454085 73454792 707 10533
hScc1 CdLSGSE12603 73454085 73454763 678 10548
hScc1 G2GSE9613 73454085 73454537 452 10661
p63 keratinocytesGSE17611 73458871 73459734 863 5669
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ETS1 JurkatGSE17954 73575858 73577141 1283 0
FOXA1 MCF7GSE15244 73500276 73501037 761 0
H3K4me3 colorectalcancer 73575867 73576114 247 0
H3ac HepG2E 73575867 73576219 352 0
NFkBII GM12878GSE19485 73559693 73561066 1373 0
NFkBII GM18526GSE19485 73560028 73561012 984 0
Nanog hESGSE18292 73549023 73549232 209 0
P300 T30-glioblastomaGSE21026 73575654 73577209 1555 0
PHF8 HeLaGSE20725 73575936 73576968 1032 0
TAF HelaGSE8489 73575867 73576091 224 0
TFAP2C MCF7GSE21234 73500138 73500707 569 0
VDR GM10855-stimGSE22484 73522311 73523751 1440 0
VDR GM10861-stimGSE22484 73522272 73523546 1274 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved