AutismKB 2.0

Annotation Detail for FZD3


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Basic Information Top
Gene Symbol:FZD3 ( Fz-3,hFz3 )
Gene Full Name: frizzled homolog 3 (Drosophila)
Band: 8p21.1
Quick LinksEntrez ID:7976; OMIM: 606143; Uniprot ID:FZD3_HUMAN; ENSEMBL ID: ENSG00000104290; HGNC ID: 4041
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
42N-linked (GlcNAc...) (Potential).
265N-linked (GlcNAc...) (Potential).
356N-linked (GlcNAc...) (Potential).
507Lys-Thr-X-X-X-Trp motif, mediates
Location(AA) Modifications Resource
42N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
265N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
356N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
42N-linkedHMM predict
48N-linkedHMM predict
99S-palmitoylHMM predict
108Phosphoserine(CK2)HMM predict
356N-linkedHMM predict
521N-linkedHMM predict
556O-linkedHMM predict
557O-linkedHMM predict
562O-linkedHMM predict
624Phosphoserine(CK1)HMM predict
636Phosphoserine(CK1)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_017412
  • Location:chr8 28407691-28477877
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FOXA1 MCF7GSE15244 28406308 28407421 1113 827
PHF8 293TGSE20725 28407082 28407984 902 159
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 28407315 28408387 1072 0
ER E2-MCF7GSE14664 28467120 28467154 34 0
Gata2 K562GSE18868 28475225 28475809 584 0
Oct1 HelaGSE14283 28467120 28467149 29 0
Oct1 HelaGSE14283 28469387 28469463 76 0
hScc1 BcellGSE12603 28407805 28408387 582 0
hScc1 CdLSGSE12603 28407210 28408420 1210 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018