AutismKB 2.0

Annotation Detail for SHCBP1


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Basic Information Top
Gene Symbol:SHCBP1 ( FLJ22009,MGC26900,PAL )
Gene Full Name: SHC SH2-domain binding protein 1
Band: 16q11.2
Quick LinksEntrez ID:79801; OMIM: 611027; Uniprot ID:SHCBP_HUMAN; ENSEMBL ID: ENSG00000171241; HGNC ID: 29547
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
31Phosphoserine.
42Phosphoserine.
44Phosphoserine.
47Phosphoserine.
273Phosphoserine.
634Phosphoserine.
Location(AA) Modifications Resource
31Phosphoserine.Swiss-Prot 53.0
42Phosphoserine.Swiss-Prot 53.0
42PhosphoserinePhospho.ELM 6.0
406PhosphotyrosinePhospho.ELM 6.0
Location(AA) Modification Resource
42Phosphoserine(IKK)HMM predict
152Phosphoserine(IKK)HMM predict
217SulfotyrosineHMM predict
217Phosphotyrosine(Abl)HMM predict
217Phosphotyrosine(SRC)HMM predict
217Phosphotyrosine(EGFR)HMM predict
269Phosphoserine(IKK)HMM predict
273Phosphoserine(CK1)HMM predict
289Phosphotyrosine(INSR)HMM predict
406Phosphotyrosine(INSR)HMM predict
634Phosphoserine(PKA)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_024745
  • Location:chr16 45171970-45212784
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T0-glioblastomaGSE21026 45229023 45229574 551 16514
CTCF G2GSE9613 45214734 45215454 720 2310
CTCF G2GSE9613 45220822 45221122 300 8188
Fos K562GSE19551 45212643 45213208 565 141
NRSF pAbJurkat 45217068 45217686 618 4593
Oct1 H2O2-HelaGSE14283 45221377 45221404 27 8606
Oct1 HelaGSE14283 45221376 45221432 56 8620
Pol2 GM12878GSE19551 45224305 45224862 557 11799
TAF HelaGSE8489 45213617 45213962 345 1005
TFAP2C MCF7GSE21234 45212736 45213312 576 240
hScc1 BcellGSE12603 45214413 45214990 577 1917
p130 shRbSenescentGSE19898 45220919 45221400 481 8375
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 45199083 45199267 184 0
CTCF CD4SISSRdata 45199083 45199267 184 0
CTCF G2GSE9613 45212404 45212906 502 0
E2F4 G0GSE7516 45212074 45213001 927 0
LIN54 G0GSE7516 45212074 45213001 927 0
LIN9 G0GSE7516 45212074 45213001 927 0
LIN9 SGSE7516 45212074 45213001 927 0
Oct1 H2O2-HelaGSE14283 45186007 45186035 28 0
P300 T30-glioblastomaGSE21026 45212302 45213206 904 0
PHF8 293TGSE20725 45212094 45212946 852 0
PHF8 HeLaGSE20725 45212138 45212911 773 0
TAF HelaGSE8489 45212074 45212659 585 0
TAF k562GSE8489 45212074 45212539 465 0
TAFII hESGSE17917 45212485 45213068 583 0
hScc1 BcellGSE12603 45212504 45212906 402 0
hScc1 CdLSGSE12603 45198893 45199151 258 0
hScc1 CdLSGSE12603 45212441 45212906 465 0
p130 QuiescentGSE19898 45212200 45212933 733 0
p130 SenescentGSE19898 45212176 45212999 823 0
p130 shRbQuiescentGSE19898 45212165 45212988 823 0
p130 shRbSenescentGSE19898 45212105 45213085 980 0
p130 G0GSE7516 45212074 45213001 927 0
p130 SGSE7516 45212120 45213001 881 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018