Annotation Detail for THNSL1

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Basic Information Top

Gene Symbol:	THNSL1 ( FLJ22002,TSH1 )
Gene Full Name:	threonine synthase-like 1 (S. cerevisiae)
Band:	10p12.1
Quick Links	Entrez ID:79896; OMIM: 611260; Uniprot ID:THNS1_HUMAN; ENSEMBL ID: ENSG00000185875; HGNC ID: 26160
Relate to Another Database:	SFARIGene; denovo-db

Pathways, Diseases and Drugs

TF binding site

Post Translation Modification

PTM Sites from Uniprot:2 results
Experimental PTM Sites from dbPTM:0 results
Predicted PTM Sites by profile HMM from dbPTM:0 results

Location(AA)	Modification
281	N6-acetyllysine.
351	N6-(pyridoxal phosphate)lysine (By

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

RefSeq ID: NM_024838
Location:chr10 25345592-25354457
strand:+

Upstream the gene:2 results
Downstream the gene:2 results
Inside the gene:10 results

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
USF2	HepG2	E	25344049	25346791	2742	173
p130	shRbSenescent	GSE19898	25344673	25345999	1326	257

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
ER	Fulvestrant-MCF7	GSE14664	25360848	25360896	48	6415
TFAP2C	MCF7	GSE21234	25365691	25366056	365	11416

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
H3ac	HepG2	E	25345988	25346899	911	0
Oct4	hES	GSE17917	25345892	25346142	250	0
PHF8	293T	GSE20725	25345273	25346582	1309	0
PHF8	HeLa	GSE20725	25345004	25346278	1274	0
PHF8	Hs68plusFBS	GSE20725	25345161	25346384	1223	0
Rb	Growing	GSE19898	25345546	25345777	231	0
Rb	Quiescent	GSE19898	25345558	25345924	366	0
hScc1	Bcell	GSE12603	25345575	25346145	570	0
p130	Quiescent	GSE19898	25346057	25346257	200	0
p130	Senescent	GSE19898	25345245	25346169	924	0

Validated miRNA targets

Cis-Nats regulation

Cluster ID	Plue Type	Plus Gene Name	Plus Chromosome	Plus Start	Plus End	Overlap Length	Minus Type	Minus Gene Name	Minus Chromosome	Minus Star	Minus End	Type
2916	mRNA	THNSL1	chr10	25345592	25354458	35	mRNA		chr10	25342204	25345912	Sense/Antisense (SA) pairs

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

Studies: 1,036
Genes: 1,379
CNVs/SVs: 5,420
SNVs/Indels: 11,669
de novo Mutations: 5,669
Mosaics: 789
Linkage Regions: 172

Paper Collected: 6/30/2018

Last Update: 8/26/2018

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