AutismKB 2.0

Annotation Detail for DOK3


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Basic Information Top
Gene Symbol:DOK3 ( DOKL,FLJ22570,FLJ39939 )
Gene Full Name: docking protein 3
Band: 5q35.3
Quick LinksEntrez ID:79930; OMIM: 611435; Uniprot ID:DOK3_HUMAN; ENSEMBL ID: ENSG00000146094; HGNC ID: 24583
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
330Phosphoserine.
381Phosphotyrosine (By similarity).
477N6-acetyllysine.
Location(AA) Modifications Resource
208PhosphotyrosinePhospho.ELM 6.0
381PhosphotyrosinePhospho.ELM 6.0
432PhosphotyrosinePhospho.ELM 6.0
453PhosphotyrosinePhospho.ELM 6.0
Location(AA) Modification Resource
38O-linkedHMM predict
38O-linkedHMM predict
40Phosphoserine(CK1)HMM predict
43Phosphoserine(MAPK)HMM predict
148Phosphothreonine(PKA)HMM predict
186O-linkedHMM predict
187O-linkedHMM predict
189Phosphoserine(IKK)HMM predict
190Phosphothreonine(CK2)HMM predict
190O-linkedHMM predict
208SulfotyrosineHMM predict
208Phosphotyrosine(INSR)HMM predict
266MethyllysineHMM predict
271MethyllysineHMM predict
284Phosphoserine(IKK)HMM predict
330Phosphoserine(IKK)HMM predict
336Phosphothreonine(MAPK)HMM predict
423O-linkedHMM predict
425Phosphoserine(CDC2)HMM predict
425O-linkedHMM predict
425Phosphoserine(IKK)HMM predict
427Phosphothreonine(PKC)HMM predict
429O-linkedHMM predict
432Phosphotyrosine(INSR)HMM predict
439Phosphoserine(IKK)HMM predict
496ProlineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_024872
  • Location:chr5 176863357-176869458
  • strand:-
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 176860675 176860934 259 2553
CTCF CD4SISSRdata 176860675 176860934 259 2553
CTCF G2GSE9613 176861625 176862188 563 1451
CTCF G2GSE9613 176862623 176863149 526 472
Rb GrowingGSE19898 176860336 176860558 222 2911
Rb GrowingGSE19898 176860576 176860732 156 2704
TFAP2C MCF7GSE21234 176860553 176860917 364 2623
hScc1 CdLSGSE12603 176860456 176861061 605 2599
p130 SenescentGSE19898 176860325 176860788 463 2801
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 176863412 176864607 1195 0
CTCF G2GSE9613 176865001 176865227 226 0
CTCF G2GSE9613 176868574 176869935 1361 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018