AutismKB 2.0

Annotation Detail for EDC3


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Basic Information Top
Gene Symbol:EDC3 ( FLJ21128,FLJ31777,LSM16,YJDC,YJEFN2 )
Gene Full Name: enhancer of mRNA decapping 3 homolog (S. cerevisiae)
Band: 15q24.1
Quick LinksEntrez ID:80153; OMIM: 609842; Uniprot ID:EDC3_HUMAN; ENSEMBL ID: ENSG00000179151; HGNC ID: 26114
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
131Phosphoserine.
161Phosphoserine.
Location(AA) Modifications Resource
131Phosphoserine.Swiss-Prot 53.0
Location(AA) Modification Resource
26Phosphoserine(PKG)HMM predict
34O-linkedHMM predict
98N-linkedHMM predict
109Phosphoserine(CK2)HMM predict
110O-linkedHMM predict
112Phosphoserine(IKK)HMM predict
112Phosphoserine(CK1)HMM predict
131Phosphoserine(CDK)HMM predict
150Phosphoserine(ATM)HMM predict
154Phosphoserine(PKC)HMM predict
161Phosphoserine(PKB)HMM predict
161Phosphoserine(IKK)HMM predict
165Phosphoserine(CDC2)HMM predict
231Phosphothreonine(PKC)HMM predict
266N-linkedHMM predict
386Phosphoserine(CK1)HMM predict
402Phosphoserine(MAPK)HMM predict
402Phosphoserine(CDC2)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_025083
  • Location:chr15 72709952-72775412
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
E2F4 G0GSE7516 72774831 72776232 1401 119
E2F4 SGSE7516 72775299 72776030 731 252
ETS1 JurkatGSE17954 72774745 72776227 1482 74
H3K4me3 colorectalcancer 72775659 72776194 535 514
LIN54 G0GSE7516 72775048 72776159 1111 191
Nanog ESGSE20650 72775232 72775969 737 188
P300 T30-glioblastomaGSE21026 72774834 72776026 1192 18
Rb GrowingGSE19898 72775446 72775580 134 101
Rb QuiescentGSE19898 72775350 72775753 403 139
Rb SenescentGSE19898 72775377 72775847 470 200
TAFII hESGSE17917 72775286 72775828 542 145
p130 QuiescentGSE19898 72775212 72776179 967 283
p130 SenescentGSE19898 72775041 72775896 855 56
p130 shRbQuiescentGSE19898 72774927 72776219 1292 161
p130 shRbSenescentGSE19898 72775167 72776087 920 215
p130 G0GSE7516 72774764 72776232 1468 86
p130 SGSE7516 72775263 72776232 969 335
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 72711337 72711683 346 0
CTCF CD4GSE12889 72714609 72714898 289 0
CTCF CD4SISSRdata 72711337 72711683 346 0
CTCF CD4SISSRdata 72714609 72714898 289 0
CTCF HelaGSE12889 72711435 72711678 243 0
CTCF JurkatGSE12889 72711401 72711617 216 0
CTCF G2GSE9613 72711122 72712094 972 0
CTCF G2GSE9613 72714031 72715177 1146 0
CTCF G2GSE9613 72722123 72722457 334 0
CTCF G2GSE9613 72775112 72775594 482 0
ER E2-MCF7GSE14664 72717638 72717675 37 0
GABP HelaGSE8489 72774235 72775370 1135 0
GABP k562GSE8489 72774235 72776232 1997 0
H3K4me2 HCT116GSE10453 72774273 72775230 957 0
H3K4me3 colorectalcancer 72774444 72775076 632 0
H3ac HepG2E 72774235 72776159 1924 0
LIN9 G0GSE7516 72774551 72776232 1681 0
LIN9 SGSE7516 72774618 72776194 1576 0
Oct1 HelaGSE14283 72714265 72714349 84 0
Oct1 HelaGSE14283 72717783 72717823 40 0
Oct1 HelaGSE14283 72762865 72762892 27 0
PHF8 293TGSE20725 72774833 72775922 1089 0
TAF HelaGSE8489 72721768 72722865 1097 0
TAF HelaGSE8489 72774481 72775191 710 0
hScc1 BcellGSE12603 72710469 72711696 1227 0
hScc1 BcellGSE12603 72714066 72715441 1375 0
hScc1 BcellGSE12603 72774977 72775839 862 0
hScc1 CdLSGSE12603 72711158 72711556 398 0
hScc1 CdLSGSE12603 72714423 72715247 824 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
9066 HTC chr15 72695257 72724807 154 mRNA FLJ21128 chr15 72709952 72775413Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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