AutismKB 2.0

Annotation Detail for MUS81


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Basic Information Top
Gene Symbol:MUS81 ( FLJ21012,FLJ44872,SLX3 )
Gene Full Name: MUS81 endonuclease homolog (S. cerevisiae)
Band: 11q13
Quick LinksEntrez ID:80198; OMIM: 606591; Uniprot ID:MUS81_HUMAN; ENSEMBL ID: ENSG00000172732; HGNC ID: 29814
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
95Phosphoserine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
97O-linkedHMM predict
97Phosphoserine(CK1)HMM predict
97Phosphoserine(IKK)HMM predict
101Phosphoserine(CDC2)HMM predict
178O-linkedHMM predict
204Phosphoserine(PKG)HMM predict
299Phosphothreonine(PKC)HMM predict
366Phosphotyrosine(Jak)HMM predict
376N-linkedHMM predict
497Phosphotyrosine(Jak)HMM predict
499Phosphothreonine(CDK)HMM predict
512Phosphothreonine(MAPK)HMM predict
551ThreonineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_025128
  • Location:chr11 65384524-65390481
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3ac HepG2E 65383638 65384461 823 475
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3ac HepG2E 65385153 65387019 1866 0
p130 shRbQuiescentGSE19898 65384508 65385353 845 0
p130 shRbSenescentGSE19898 65384708 65385099 391 0
p130 shRbSenescentGSE19898 65389436 65389744 308 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018