AutismKB 2.0

Annotation Detail for LHX3


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Basic Information Top
Gene Symbol:LHX3 ( CPHD3,DKFZp762A2013,LIM3,M2-LHX3 )
Gene Full Name: LIM homeobox 3
Band: 9q34.3
Quick LinksEntrez ID:8022; OMIM: 600577; Uniprot ID:LHX3_HUMAN; ENSEMBL ID: ENSG00000107187; HGNC ID: 6595
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
132Phosphotyrosine(Syk)HMM predict
162Phosphothreonine(PKA)HMM predict
178Phosphothreonine(PKC)HMM predict
179Phosphoserine(CDC2)HMM predict
192Phosphoserine(CK1)HMM predict
235MethylarginineHMM predict
251Phosphoserine(CK2)HMM predict
262Phosphoserine(IKK)HMM predict
306Phosphotyrosine(EGFR)HMM predict
313Phosphoserine(CDC2)HMM predict
315Phosphotyrosine(Abl)HMM predict
320Phosphoserine(CDC2)HMM predict
320O-linkedHMM predict
320PhosphoserineHMM predict
320Phosphoserine(IKK)HMM predict
320Phosphoserine(ATM)HMM predict
326Phosphoserine(IKK)HMM predict
359MethylarginineHMM predict
371Phosphoserine(CK1)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_014564
  • Location:chr9 138227918-138234824
  • strand:-
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
hScc1 BcellGSE12603 138214388 138214830 442 13310
hScc1 BcellGSE12603 138217968 138218387 419 9741
hScc1 BcellGSE12603 138224445 138226215 1770 2589
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
NRSF JurkatGSE13047 138233320 138233794 474 0
NRSF-mono JurkatQuESTdata 138233356 138233850 494 0
NRSF-poly JurkatQuESTdata 138233169 138233794 625 0
TFAP2C MCF7GSE21234 138228411 138228979 568 0
hScc1 BcellGSE12603 138233590 138235292 1702 0
p63 keratinocytesGSE17611 138230160 138230835 675 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018