AutismKB 2.0

Annotation Detail for PREX2


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Basic Information Top
Gene Symbol:PREX2 ( 6230420N16Rik,DEP.2,DEPDC2,P-REX2 )
Gene Full Name: phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
Band: 8q13.2
Quick LinksEntrez ID:80243; OMIM: 612139; Uniprot ID:PREX2_HUMAN; ENSEMBL ID: ENSG00000046889; HGNC ID: 22950
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_024870
  • Location:chr8 69027156-69306450
  • strand:+
No data
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Myc K562GSE19551 69227447 69228010 563 0
NRSF JurkatGSE13047 69246796 69247582 786 0
NRSF JurkatSISSRdata 69247025 69247388 363 0
NRSF mAbJurkat 69243986 69245111 1125 0
NRSF mAbJurkat 69245987 69248614 2627 0
NRSF mAbJurkat 69248974 69250162 1188 0
NRSF-mono JurkatQuESTdata 69246905 69247581 676 0
NRSF-poly JurkatQuESTdata 69246975 69247478 503 0
Nanog hESGSE18292 69239702 69240126 424 0
Oct1 H2O2-HelaGSE14283 69241618 69241708 90 0
Oct1 HelaGSE14283 69181708 69181747 39 0
Oct1 HelaGSE14283 69185269 69185336 67 0
Oct1 HelaGSE14283 69241584 69241717 133 0
Oct4 ESGSE20650 69276529 69276698 169 0
Sox2 hESGSE18292 69285323 69285494 171 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
25550 mRNA DEPDC2 chr8 69027156 69306451 167 HTC chr8 69306284 69311819Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018