Annotation Detail for EDEM3
Basic Information Top
| Gene Symbol: | EDEM3 ( C1orf22 ) |
|---|---|
| Gene Full Name: | ER degradation enhancer, mannosidase alpha-like 3 |
| Band: | 1q25.3 |
| Quick Links | Entrez ID:80267; OMIM: 610214; Uniprot ID:EDEM3_HUMAN; ENSEMBL ID: ENSG00000116406; HGNC ID: 16787 |
| Relate to Another Database: | SFARIGene; denovo-db |
| Location(AA) | Modification | |
|---|---|---|
| 118 | N-linked (GlcNAc...) (Potential). | |
| 195 | N-linked (GlcNAc...). | |
| 303 | Phosphotyrosine (By similarity). | |
| 310 | Phosphoserine (By similarity). | |
| 504 | N-linked (GlcNAc...) (Potential). | |
| 511 | N-linked (GlcNAc...) (Potential). | |
| 810 | N-linked (GlcNAc...) (Potential). | |
| 814 | N-linked (GlcNAc...) (Potential). | |
| 900 | N-linked (GlcNAc...) (Potential). | |
| 932 | Prevents secretion from ER (Potential). | |
| Location(AA) | Modifications | Resource |
|---|---|---|
| 75 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 |
| 152 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 |
| 461 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 |
| 468 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 |
| 767 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 |
| 771 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 |
| 857 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 |
| Location(AA) | Modification | Resource |
|---|---|---|
| 21 | Sulfotyrosine | HMM predict |
| 24 | Sulfotyrosine | HMM predict |
| 29 | Sulfotyrosine | HMM predict |
| 75 | N-linked | HMM predict |
| 128 | Sulfotyrosine | HMM predict |
| 128 | Phosphotyrosine(INSR) | HMM predict |
| 152 | N-linked | HMM predict |
| 155 | O-linked | HMM predict |
| 181 | O-linked | HMM predict |
| 267 | Phosphoserine(CK2) | HMM predict |
| 284 | Phosphoserine(ATM) | HMM predict |
| 379 | Phosphotyrosine(Syk) | HMM predict |
| 444 | Sulfotyrosine | HMM predict |
| 468 | N-linked | HMM predict |
| 469 | Phosphothreonine(CK2) | HMM predict |
| 469 | Phosphothreonine(PKC) | HMM predict |
| 473 | Phosphotyrosine(INSR) | HMM predict |
| 594 | Phosphoserine(ATM) | HMM predict |
| 637 | Phosphothreonine(PKA) | HMM predict |
| 697 | Phosphoserine(CK1) | HMM predict |
| 697 | Phosphoserine(CK2) | HMM predict |
| 699 | Phosphoserine(ATM) | HMM predict |
| 764 | Phosphoserine(CK1) | HMM predict |
| 764 | Phosphoserine(CK2) | HMM predict |
| 765 | Phosphoserine(CK2) | HMM predict |
| 765 | Phosphoserine | HMM predict |
| 765 | Phosphoserine(IKK) | HMM predict |
| 767 | N-linked | HMM predict |
| 769 | Phosphoserine(CK1) | HMM predict |
| 769 | Phosphoserine(ATM) | HMM predict |
| 769 | Phosphoserine(IKK) | HMM predict |
| 771 | N-linked | HMM predict |
| 781 | Phosphoserine(ATM) | HMM predict |
| 791 | Phosphoserine(CK1) | HMM predict |
| 792 | Phosphoserine(CK1) | HMM predict |
| 792 | Phosphoserine(CK2) | HMM predict |
| 796 | Phosphoserine(CK1) | HMM predict |
| 805 | Phosphoserine(IKK) | HMM predict |
| 816 | Phosphoserine(MAPK) | HMM predict |
| 818 | O-linked | HMM predict |
| 818 | O-linked | HMM predict |
| 822 | Phosphoserine(IKK) | HMM predict |
| 823 | N-linked | HMM predict |
| 827 | N-linked | HMM predict |
| 848 | Phosphoserine(CK2) | HMM predict |
- RefSeq ID: NM_025191
- Location:chr1 182926260-182990326
- strand:-
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| CTCF | G2 | GSE9613 | 182989900 | 182990950 | 1050 | 99 |
| ETS1 | Jurkat | GSE17954 | 182989714 | 182991443 | 1729 | 252 |
| Fos | K562 | GSE19551 | 182990363 | 182991797 | 1434 | 754 |
| H3K4me2 | HCT116 | GSE10453 | 182990971 | 182991746 | 775 | 1032 |
| H3K4me3 | colorectal | cancer | 182991199 | 182991783 | 584 | 1165 |
| H3ac | HepG2 | E | 182991164 | 182991783 | 619 | 1147 |
| Myc | K562 | GSE19551 | 183006950 | 183007341 | 391 | 16819 |
| Oct1 | Hela | GSE14283 | 182992897 | 182992925 | 28 | 2585 |
| PHF8 | Hs68minusFBS | GSE20725 | 182989941 | 182991551 | 1610 | 420 |
| RARA | MCF7 | GSE15244 | 182991199 | 182991698 | 499 | 1122 |
| Rb | Quiescent | GSE19898 | 182990625 | 182990968 | 343 | 470 |
| Rb | Quiescent | GSE19898 | 182990975 | 182991246 | 271 | 784 |
| Rb | Senescent | GSE19898 | 182990627 | 182991164 | 537 | 569 |
| TAF | k562 | GSE8489 | 182991199 | 182992294 | 1095 | 1420 |
| TAF | k562 | GSE8489 | 183005908 | 183006450 | 542 | 15853 |
| hScc1 | Bcell | GSE12603 | 182989936 | 182990758 | 822 | 21 |
| p130 | Quiescent | GSE19898 | 182990578 | 182991010 | 432 | 468 |
| p130 | Senescent | GSE19898 | 182990534 | 182991076 | 542 | 479 |
| p130 | shRbQuiescent | GSE19898 | 182990697 | 182991068 | 371 | 556 |
| p130 | shRbSenescent | GSE19898 | 182990434 | 182990999 | 565 | 390 |
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| TFAP2C | MCF7 | GSE21234 | 182920733 | 182921167 | 434 | 5311 |
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| ER | Fulvestrant-MCF7 | GSE14664 | 182946408 | 182946453 | 45 | 0 |
| H3ac | HepG2 | E | 182989666 | 182990167 | 501 | 0 |
| Oct1 | Hela | GSE14283 | 182946410 | 182946459 | 49 | 0 |
Validated miRNA targets