AutismKB 2.0

Annotation Detail for CCDC6


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Basic Information Top
Gene Symbol:CCDC6 ( D10S170,FLJ32286,H4,PTC,TPC,TST1 )
Gene Full Name: coiled-coil domain containing 6
Band: 10q21.2
Quick LinksEntrez ID:8030; OMIM: 601985; Uniprot ID:CCDC6_HUMAN; ENSEMBL ID: ENSG00000108091; HGNC ID: 18782
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
2N-acetylalanine.
52Phosphoserine.
113Phosphoserine.
115Phosphothreonine.
240Phosphoserine.
244Phosphoserine.
249Phosphoserine.
254Phosphoserine.
323Phosphoserine.
325Phosphoserine.
328Phosphoserine.
349Phosphothreonine.
351Phosphoserine.
352Phosphoserine.
356Phosphotyrosine.
363Phosphoserine.
367Phosphoserine.
371Phosphoserine.
372Phosphotyrosine.
376Phosphothreonine.
419Phosphoserine.
451SH3-binding (Potential).
Location(AA) Modifications Resource
52Phosphoserine.Swiss-Prot 53.0
240Phosphoserine.Swiss-Prot 53.0
240PhosphoserinePhospho.ELM 6.0
244Phosphoserine.Swiss-Prot 53.0
244PhosphoserinePhospho.ELM 6.0
323Phosphoserine.Swiss-Prot 53.0
325Phosphoserine.Swiss-Prot 53.0
328Phosphoserine.Swiss-Prot 53.0
Location(AA) Modification Resource
6Phosphoserine(IKK)HMM predict
6Phosphoserine(CK1)HMM predict
16N-linkedHMM predict
20O-linkedHMM predict
28Phosphoserine(CK1)HMM predict
29Phosphoserine(CK1)HMM predict
30O-linkedHMM predict
98Phosphoserine(PKG)HMM predict
183N-linkedHMM predict
244Phosphoserine(CDC2)HMM predict
323Phosphoserine(CAMK2)HMM predict
327Phosphoserine(IKK)HMM predict
328Phosphoserine(CK1)HMM predict
336SulfotyrosineHMM predict
351Phosphoserine(IKK)HMM predict
351O-linkedHMM predict
352O-linkedHMM predict
352Phosphoserine(CDC2)HMM predict
357O-linkedHMM predict
357Phosphothreonine(MAPK)HMM predict
359Phosphoserine(IKK)HMM predict
359Phosphoserine(CDC2)HMM predict
363O-linkedHMM predict
367Phosphoserine(MAPK)HMM predict
380Phosphothreonine(MAPK)HMM predict
413Phosphoserine(CDC2)HMM predict
413PhosphoserineHMM predict
413Phosphoserine(CDK)HMM predict
417Phosphoserine(PKG)HMM predict
419Phosphoserine(CDC2)HMM predict
427Phosphothreonine(MAPK)HMM predict
427PhosphothreonineHMM predict
427Phosphothreonine(PKA)HMM predict
431O-linkedHMM predict
436Phosphothreonine(CDC2)HMM predict
436Phosphothreonine(CDK)HMM predict
452O-linkedHMM predict
538N-linkedHMM predict
541O-linkedHMM predict
554Phosphoserine(CK1)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_005436
  • Location:chr10 61218527-61336313
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3K4me3 colorectalcancer 61337607 61337971 364 1476
H3ac HepG2E 61336889 61338500 1611 1381
PHF8 HeLaGSE20725 61335542 61337234 1692 75
RARA MCF7GSE15244 61336814 61337438 624 813
RARG MCF7GSE15244 61336850 61337259 409 741
Rb SenescentGSE19898 61336191 61336640 449 102
TAF k562GSE8489 61336889 61338567 1678 1415
p130 shRbSenescentGSE19898 61336157 61336775 618 153
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Oct1 H2O2-HelaGSE14283 61205403 61205442 39 13105
Oct1 HelaGSE14283 61205400 61205442 42 13107
Oct1 HelaGSE14283 61212653 61212714 61 5844
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 61239141 61239441 300 0
CTCF CD4GSE12889 61294949 61295172 223 0
CTCF CD4SISSRdata 61239141 61239441 300 0
CTCF CD4SISSRdata 61294949 61295172 223 0
CTCF HelaGSE12889 61239126 61239518 392 0
CTCF JurkatGSE12889 61239201 61239393 192 0
ER E2-MCF7GSE14664 61237965 61238043 78 0
ER Fulvestrant-MCF7GSE14664 61238971 61239004 33 0
ER MCF7GSE19013 61265005 61265662 657 0
ER MCF7GSE19013 61268817 61269247 430 0
FOXA1 MCF7GSE15244 61269033 61269265 232 0
H3K4me2 HCT116GSE10453 61333849 61335165 1316 0
H3K4me3 colorectalcancer 61334040 61335130 1090 0
H3ac HepG2E 61333293 61335636 2343 0
KLF4 hESGSE17917 61251154 61251322 168 0
Myc K562GSE19551 61310560 61311253 693 0
Myc K562GSE19551 61325433 61325893 460 0
NFkBII GM10847GSE19485 61308954 61311820 2866 0
NFkBII GM12878GSE19485 61308713 61311936 3223 0
NFkBII GM12892GSE19485 61308859 61311874 3015 0
NFkBII GM15510GSE19485 61308968 61311850 2882 0
Nanog hESGSE18292 61277092 61277562 470 0
Oct1 H2O2-HelaGSE14283 61294345 61294396 51 0
Oct1 H2O2-HelaGSE14283 61301300 61301327 27 0
Oct1 H2O2-HelaGSE14283 61325086 61325118 32 0
Oct1 HelaGSE14283 61294333 61294406 73 0
Oct1 HelaGSE14283 61301281 61301338 57 0
Oct1 HelaGSE14283 61323812 61323859 47 0
P300 T30-glioblastomaGSE21026 61302631 61303468 837 0
RARA MCF7GSE15244 61269033 61269265 232 0
RARA MCF7GSE15244 61321006 61321995 989 0
RARG MCF7GSE15244 61247935 61248187 252 0
RARG MCF7GSE15244 61269033 61269265 232 0
RARG MCF7GSE15244 61284054 61284705 651 0
RARG MCF7GSE15244 61294252 61295086 834 0
RARG MCF7GSE15244 61299715 61300106 391 0
RARG MCF7GSE15244 61302413 61302626 213 0
RARG MCF7GSE15244 61321006 61321848 842 0
RARG MCF7GSE15244 61329668 61329976 308 0
STAT1 HeLaGSE12783 61294577 61296032 1455 0
STAT1 IFNSISSRdata 61294790 61295408 618 0
TFAP2C MCF7GSE21234 61277665 61277995 330 0
hScc1 BcellGSE12603 61239013 61239699 686 0
hScc1 BcellGSE12603 61294531 61295294 763 0
hScc1 BcellGSE12603 61299270 61299800 530 0
hScc1 BcellGSE12603 61334947 61337047 2100 0
hScc1 CdLSGSE12603 61238904 61239699 795 0
hScc1 CdLSGSE12603 61294719 61295294 575 0
hScc1 CdLSGSE12603 61315076 61315444 368 0
hScc1 CdLSGSE12603 61334877 61337146 2269 0
hScc1 G2GSE9613 61239084 61239663 579 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-146a hsa-mir-146a 5 18474871
hsa-miR-146a* hsa-mir-146a 5 18474871
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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