AutismKB 2.0

Annotation Detail for PLEKHO2


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Basic Information Top
Gene Symbol:PLEKHO2 ( DKFZp761K2312,FLJ38884,PLEKHQ1,PP1628,pp9099 )
Gene Full Name: pleckstrin homology domain containing, family O member 2
Band: 15q22.31
Quick LinksEntrez ID:80301; OMIM: NA; Uniprot ID:PKHO2_HUMAN; ENSEMBL ID: ENSG00000166839,ENSG00000241839; HGNC ID: 30026
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
232Phosphothreonine (By similarity).
235Phosphoserine (By similarity).
278Phosphoserine (By similarity).
390Phosphoserine (By similarity).
468Phosphoserine.
Location(AA) Modifications Resource
No data
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_025201
  • Location:chr15 62921187-62947251
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 62914969 62915361 392 6023
CTCF CD4SISSRdata 62914969 62915361 392 6023
CTCF G2GSE9613 62920655 62920996 341 362
Fos K562GSE19551 62914703 62915299 596 6187
Myc K562GSE19551 62914884 62915421 537 6035
NFkBII GM12892GSE19485 62920204 62921789 1585 191
Oct1 H2O2-HelaGSE14283 62914240 62914270 30 6933
Oct1 HelaGSE14283 62914240 62914270 30 6933
PHF8 HeLaGSE20725 62920024 62921836 1812 258
Rb SenescentGSE19898 62920735 62921162 427 239
TFAP2C MCF7GSE21234 62914839 62915404 565 6066
hScc1 BcellGSE12603 62915013 62915778 765 5792
hScc1 BcellGSE12603 62920265 62921251 986 430
hScc1 CdLSGSE12603 62914976 62915547 571 5926
p130 QuiescentGSE19898 62914873 62915186 313 6158
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T30-glioblastomaGSE21026 62951902 62952899 997 5149
P300 T30-glioblastomaGSE21026 62951927 62952885 958 5155
P300 T30-glioblastomaGSE21026 62962376 62964037 1661 15955
Rb SenescentGSE19898 62952367 62952600 233 5232
Rb shRbQuiescentGSE19898 62952454 62952720 266 5336
VDR GM10855-stimGSE22484 62960950 62964233 3283 15340
VDR GM10861-stimGSE22484 62961106 62964067 2961 15335
p130 SenescentGSE19898 62952333 62952799 466 5315
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T30-glioblastomaGSE21026 62944932 62946088 1156 0
CTCF G2GSE9613 62937185 62937422 237 0
CTCF G2GSE9613 62940463 62940750 287 0
CTCF G2GSE9613 62943605 62943839 234 0
CTCF G2GSE9613 62944189 62944865 676 0
ER E2-MCF7GSE14664 62944491 62944523 32 0
H3ac HepG2E 62921482 62922157 675 0
NFkBII GM12892GSE19485 62943913 62945210 1297 0
P300 T30-glioblastomaGSE21026 62945037 62945903 866 0
Pol2 GM12878GSE19551 62921105 62921747 642 0
TAF HelaGSE8489 62921779 62922258 479 0
hScc1 BcellGSE12603 62923144 62923640 496 0
hScc1 BcellGSE12603 62933180 62933901 721 0
hScc1 BcellGSE12603 62935954 62936354 400 0
p130 QuiescentGSE19898 62945619 62945887 268 0
p130 QuiescentGSE19898 62945891 62946039 148 0
p130 SenescentGSE19898 62945604 62945881 277 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018