AutismKB 2.0

Annotation Detail for NCOA4


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Basic Information Top
Gene Symbol:NCOA4 ( ARA70,DKFZp762E1112,ELE1,PTC3,RFG )
Gene Full Name: nuclear receptor coactivator 4
Band: 10q11.22
Quick LinksEntrez ID:8031; OMIM: 601984; Uniprot ID:NCOA4_HUMAN; ENSEMBL ID: ENSG00000138293; HGNC ID: 7671
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
456Phosphoserine.
Location(AA) Modifications Resource
456Phosphoserine.Swiss-Prot 53.0
456PhosphoserinePhospho.ELM 6.0
Location(AA) Modification Resource
8Phosphoserine(IKK)HMM predict
214Phosphotyrosine(Syk)HMM predict
237Phosphoserine(IKK)HMM predict
237Phosphoserine(ATM)HMM predict
269Phosphotyrosine(EGFR)HMM predict
307Phosphothreonine(CDK)HMM predict
307Phosphothreonine(MAPK)HMM predict
319N-linkedHMM predict
380Phosphoserine(IKK)HMM predict
381Phosphothreonine(MAPK)HMM predict
478Phosphothreonine(CDK)HMM predict
478Phosphothreonine(CDC2)HMM predict
478Phosphothreonine(MAPK)HMM predict
492Phosphoserine(CDC2)HMM predict
525Phosphoserine(CDC2)HMM predict
528N-linkedHMM predict
533O-linkedHMM predict
550Phosphoserine(ATM)HMM predict
553Phosphoserine(CK2)HMM predict
572Phosphoserine(MAPK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_005437
  • Location:chr10 51242372-51260737
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3ac HepG2E 51239090 51240319 1229 2668
hScc1 CdLSGSE12603 51241770 51242443 673 266
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3ac HepG2E 51244164 51245226 1062 0
PHF8 HeLaGSE20725 51241981 51242801 820 0
RARA MCF7GSE15244 51250483 51251486 1003 0
RARG MCF7GSE15244 51250555 51251343 788 0
RARG MCF7GSE15244 51254777 51255526 749 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-let-7a hsa-let-7a-1 9 19956384
hsa-let-7a hsa-let-7a-2 11 19956384
hsa-let-7a hsa-let-7a-3 22 19956384
hsa-let-7a* hsa-let-7a-1 9 19956384
hsa-let-7a* hsa-let-7a-3 22 19956384
hsa-let-7b hsa-let-7b 22 19956384
hsa-let-7b* hsa-let-7b 22 19956384
hsa-let-7c hsa-let-7c 21 19956384
hsa-let-7c* hsa-let-7c 21 19956384
hsa-let-7d hsa-let-7d 9 19956384
hsa-let-7d* hsa-let-7d 9 19956384
hsa-let-7e hsa-let-7e 19 19956384
hsa-let-7e* hsa-let-7e 19 19956384
hsa-let-7f hsa-let-7f-1 9 19956384
hsa-let-7f hsa-let-7f-2 X 19956384
hsa-let-7f-1* hsa-let-7f-1 9 19956384
hsa-let-7f-2* hsa-let-7f-2 X 19956384
hsa-let-7g hsa-let-7g 3 19956384
hsa-let-7g* hsa-let-7g 3 19956384
hsa-let-7i hsa-let-7i 12 19956384
hsa-let-7i* hsa-let-7i 12 19956384
No data
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
3146 mRNA NCOA4 chr10 51242372 51260738 360 EST chr10 51259054 51259590Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018