AutismKB 2.0

Annotation Detail for PDGFD


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Basic Information Top
Gene Symbol:PDGFD ( IEGF,MGC26867,SCDGF-B,SCDGFB )
Gene Full Name: platelet derived growth factor D
Band: 11q22.3
Quick LinksEntrez ID:80310; OMIM: 609673; Uniprot ID:PDGFD_HUMAN; ENSEMBL ID: ENSG00000170962; HGNC ID: 30620
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
276N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
276N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
21O-linkedHMM predict
24Phosphothreonine(CDK)HMM predict
24Phosphothreonine(MAPK)HMM predict
27O-linkedHMM predict
63Phosphotyrosine(EGFR)HMM predict
63Phosphotyrosine(Jak)HMM predict
156Phosphotyrosine(INSR)HMM predict
181O-linkedHMM predict
188Phosphoserine(CK1)HMM predict
189Phosphoserine(IKK)HMM predict
197Phosphoserine(CDC2)HMM predict
201O-linkedHMM predict
226Phosphotyrosine(INSR)HMM predict
240Phosphotyrosine(Syk)HMM predict
250Phosphoserine(PKB)HMM predict
270Phosphotyrosine(Jak)HMM predict
323Phosphothreonine(PKC)HMM predict
341MethylarginineHMM predict
360CysteineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_025208
  • Location:chr11 103283124-103540236
  • strand:-
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Oct1 HelaGSE14283 103274535 103274566 31 8574
Rb QuiescentGSE19898 103274053 103274279 226 8959
hScc1 CdLSGSE12603 103274033 103274304 271 8956
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T0-glioblastomaGSE21026 103316333 103317105 772 0
FOXA1 DLD1GSE12801 103364236 103364746 510 0
NFkBII GM12878GSE19485 103333905 103336157 2252 0
Nanog hESGSE18292 103330430 103330859 429 0
Nanog hESGSE18292 103527364 103527635 271 0
Oct1 H2O2-HelaGSE14283 103288865 103288901 36 0
Oct1 H2O2-HelaGSE14283 103290739 103290767 28 0
Oct1 H2O2-HelaGSE14283 103305606 103305637 31 0
Oct1 H2O2-HelaGSE14283 103380602 103380640 38 0
Oct1 H2O2-HelaGSE14283 103383976 103384005 29 0
Oct1 H2O2-HelaGSE14283 103422908 103422943 35 0
Oct1 H2O2-HelaGSE14283 103427996 103428022 26 0
Oct1 HelaGSE14283 103288866 103288902 36 0
Oct1 HelaGSE14283 103305601 103305677 76 0
Oct1 HelaGSE14283 103337540 103337569 29 0
Oct1 HelaGSE14283 103380602 103380640 38 0
Oct1 HelaGSE14283 103383974 103384019 45 0
Oct1 HelaGSE14283 103422909 103422943 34 0
Oct1 HelaGSE14283 103427992 103428022 30 0
Oct1 HelaGSE14283 103459202 103459236 34 0
Oct1 HelaGSE14283 103476201 103476268 67 0
Oct1 HelaGSE14283 103476443 103476473 30 0
Oct4 hESGSE21916 103498150 103498578 428 0
P300 T0-glioblastomaGSE21026 103316012 103317465 1453 0
P300 T0-glioblastomaGSE21026 103408705 103409905 1200 0
P300 T30-glioblastomaGSE21026 103315701 103317105 1404 0
RNAII Tamoxifen-MCF7GSE14664 103305576 103305650 74 0
Rb GrowingGSE19898 103305185 103305386 201 0
hScc1 BcellGSE12603 103303152 103303888 736 0
hScc1 BcellGSE12603 103539785 103540164 379 0
hScc1 CdLSGSE12603 103419893 103420109 216 0
hScc1 CdLSGSE12603 103527451 103527802 351 0
hScc1 CdLSGSE12603 103539748 103540126 378 0
p63 keratinocytesGSE17611 103452414 103453100 686 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-let-7d hsa-let-7d 9 21266476
hsa-let-7d* hsa-let-7d 9 21266476
hsa-miR-146b-3p hsa-mir-146b 10 21266476
hsa-miR-146b-5p hsa-mir-146b 10 21266476
hsa-miR-221 hsa-mir-221 X 19088079
hsa-miR-221* hsa-mir-221 X 19088079
No data
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
5119 mRNA DDI1 chr11 103412537 103415126 2589 mRNA PDGFD chr11 103283127 103540099 Non-exonic Bidirectional (NOB) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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