AutismKB 2.0

Annotation Detail for ADAM33


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Basic Information Top
Gene Symbol:ADAM33 ( C20orf153,DJ964F7.1,DKFZp434K0521,FLJ35308,FLJ36751,MGC149823,MGC71889 )
Gene Full Name: ADAM metallopeptidase domain 33
Band: 20p13
Quick LinksEntrez ID:80332; OMIM: 607114; Uniprot ID:ADA33_HUMAN; ENSEMBL ID: ENSG00000149451; HGNC ID: 15478
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
109N-linked (GlcNAc...) (Potential).
138Cysteine switch (By similarity).
145N-linked (GlcNAc...) (Potential).
231N-linked (GlcNAc...).
269Phosphoserine.
276N-linked (GlcNAc...).
448N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
109N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
145N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
231N-linked (GlcNAc...).Swiss-Prot 53.0
269Phosphoserine.Swiss-Prot 53.0
276N-linked (GlcNAc...).Swiss-Prot 53.0
448N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
11Phosphothreonine(PKA)HMM predict
41Phosphothreonine(MAPK)HMM predict
61Phosphoserine(IKK)HMM predict
109N-linkedHMM predict
162Phosphoserine(CK1)HMM predict
200MethylarginineHMM predict
208Phosphothreonine(PKC)HMM predict
215Phosphotyrosine(INSR)HMM predict
231N-linkedHMM predict
272Phosphothreonine(PKA)HMM predict
276N-linkedHMM predict
342Phosphothreonine(PKC)HMM predict
448N-linkedHMM predict
466S-palmitoylHMM predict
491O-linkedHMM predict
786Phosphoserine(CK2)HMM predict
797Phosphoserine(CDK)HMM predict
797Phosphoserine(MAPK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_025220
  • Location:chr20 3596620-3610737
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3K27me3 colorectalcancer 3612089 3612381 292 1498
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP JurkatGSE17954 3593954 3595646 1692 1821
Nanog hESGSE18292 3595679 3595970 291 796
Sox2 hESGSE18292 3595689 3595908 219 822
TFAP2C MCF7GSE21234 3594509 3595200 691 1766
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 3605375 3605633 258 0
CTCF CD4SISSRdata 3605375 3605633 258 0
CTCF JurkatGSE12889 3605330 3605545 215 0
ER MCF7GSE19013 3600948 3601556 608 0
Rb shRbQuiescentGSE19898 3606721 3606917 196 0
TFAP2C MCF7GSE21234 3605198 3605681 483 0
hScc1 BcellGSE12603 3599716 3600007 291 0
hScc1 BcellGSE12603 3600658 3601453 795 0
hScc1 BcellGSE12603 3601732 3603098 1366 0
hScc1 BcellGSE12603 3605365 3605770 405 0
hScc1 BcellGSE12603 3606375 3606514 139 0
hScc1 BcellGSE12603 3608640 3609115 475 0
hScc1 BcellGSE12603 3610317 3610921 604 0
hScc1 CdLSGSE12603 3605365 3605704 339 0
p130 SenescentGSE19898 3605375 3605628 253 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018