AutismKB 2.0

Annotation Detail for REEP4


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Basic Information Top
Gene Symbol:REEP4 ( C8orf20,FLJ22246,FLJ22277 )
Gene Full Name: receptor accessory protein 4
Band: 8p21.3
Quick LinksEntrez ID:80346; OMIM: 609349; Uniprot ID:REEP4_HUMAN; ENSEMBL ID: ENSG00000168476; HGNC ID: 26176
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
152Phosphoserine.
194Phosphoserine.
196Phosphothreonine.
202Phosphoserine.
250Phosphothreonine.
253Phosphoserine.
Location(AA) Modifications Resource
152Phosphoserine.Swiss-Prot 53.0
152PhosphoserinePhospho.ELM 6.0
194Phosphoserine.Swiss-Prot 53.0
194PhosphoserinePhospho.ELM 6.0
196Phosphothreonine.Swiss-Prot 53.0
196PhosphothreoninePhospho.ELM 6.0
202Phosphoserine.Swiss-Prot 53.0
202PhosphoserinePhospho.ELM 6.0
Location(AA) Modification Resource
106Phosphotyrosine(Jak)HMM predict
115Phosphotyrosine(EGFR)HMM predict
150Phosphoserine(CAMK2)HMM predict
158Phosphoserine(CK1)HMM predict
187MethylarginineHMM predict
194Phosphoserine(CK2)HMM predict
194Phosphoserine(CK2)HMM predict
196Phosphothreonine(CK2)HMM predict
238Phosphothreonine(PKA)HMM predict
238Phosphothreonine(PKC)HMM predict
250Phosphothreonine(PKC)HMM predict
250Phosphothreonine(PKA)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_025232
  • Location:chr8 22051477-22055392
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 22056814 22057211 397 1620
FOXA1 MCF7GSE15244 22056916 22057713 797 1922
TFAP2C MCF7GSE21234 22057020 22057786 766 2011
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 22050770 22051182 412 502
CTCF CD4SISSRdata 22050770 22051182 412 502
CTCF G2GSE9613 22047447 22048192 745 3658
CTCF G2GSE9613 22050467 22051040 573 724
Rb shRbSenescenceGSE19898 22048854 22048971 117 2565
hScc1 BcellGSE12603 22050368 22051383 1015 602
hScc1 CdLSGSE12603 22050331 22051348 1017 638
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 22051284 22051886 602 0
CTCF G2GSE9613 22052784 22053932 1148 0
CTCF G2GSE9613 22054923 22055387 464 0
E2F4 G0GSE7516 22054731 22055569 838 0
FOXA1 MCF7GSE15244 22054147 22054840 693 0
H3ac HepG2E 22053488 22054109 621 0
LIN54 G0GSE7516 22054803 22055533 730 0
LIN9 G0GSE7516 22054579 22055666 1087 0
PHF8 293TGSE20725 22054379 22055593 1214 0
p130 G0GSE7516 22054654 22055569 915 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018