AutismKB 2.0

Annotation Detail for CUL5


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Basic Information Top
Gene Symbol:CUL5 ( VACM-1,VACM1 )
Gene Full Name: cullin 5
Band: 11q22.3
Quick LinksEntrez ID:8065; OMIM: 601741; Uniprot ID:CUL5_HUMAN; ENSEMBL ID: ENSG00000166266; HGNC ID: 2556
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
210Phosphothreonine.
Location(AA) Modifications Resource
372PhosphotyrosinePhospho.ELM 6.0
724Glycyl lysine isopeptide (Lys-Gly)(interchain with G-Cter in NEDD8) (Bysimilarity).Swiss-Prot 53.0
729Phosphoserine (PKA
Location(AA) Modification Resource
34Phosphoserine(PKG)HMM predict
144N-linkedHMM predict
150N-linkedHMM predict
183Phosphoserine(PKG)HMM predict
288N-linkedHMM predict
334O-linkedHMM predict
335Phosphothreonine(CK2)HMM predict
426Phosphothreonine(PKC)HMM predict
426Phosphothreonine(CK2)HMM predict
470Phosphoserine(CK2)HMM predict
565N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_003478
  • Location:chr11 107384617-107483693
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Myc K562GSE19551 107375750 107376005 255 8740
NRSF JurkatGSE13047 107379623 107379889 266 4862
NRSF JurkatSISSRdata 107379659 107379885 226 4846
NRSF mAbJurkat 107379048 107379696 648 5246
NRSF-mono JurkatQuESTdata 107379622 107379884 262 4865
NRSF-poly JurkatQuESTdata 107379518 107380007 489 4855
Nanog ESGSE20650 107367747 107368364 617 16562
Nanog hESGSE18292 107367741 107368223 482 16636
USF1 HepG2E 107383374 107383653 279 1104
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Oct1 HelaGSE14283 107490247 107490279 32 6570
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 107384575 107384972 397 0
CTCF CD4SISSRdata 107384575 107384972 397 0
FOXA1 MCF7GSE15244 107404971 107405336 365 0
H3ac HepG2E 107385006 107386332 1326 0
KLF4 hESGSE17917 107414039 107414194 155 0
Myc K562GSE19551 107395767 107396266 499 0
Oct1 H2O2-HelaGSE14283 107432092 107432119 27 0
Oct1 HelaGSE14283 107432080 107432118 38 0
PHF8 293TGSE20725 107384495 107385750 1255 0
PHF8 HeLaGSE20725 107384566 107385705 1139 0
PHF8 Hs68minusFBSGSE20725 107384438 107385885 1447 0
PHF8 Hs68plusFBSGSE20725 107384480 107385991 1511 0
Rb QuiescentGSE19898 107384654 107384957 303 0
TAF HelaGSE8489 107385354 107385770 416 0
USF1 HepG2E 107384027 107386332 2305 0
hScc1 BcellGSE12603 107384312 107384922 610 0
hScc1 CdLSGSE12603 107384422 107384963 541 0
p130 QuiescentGSE19898 107384763 107385774 1011 0
p130 SenescentGSE19898 107384700 107385739 1039 0
p130 shRbQuiescentGSE19898 107384602 107385778 1176 0
p130 shRbSenescentGSE19898 107384814 107385784 970 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
5149 mRNA CUL5 chr11 107384854 107482773 342 EST chr11 107481664 107482771Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018