AutismKB 2.0

Annotation Detail for PTP4A2


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Basic Information Top
Gene Symbol:PTP4A2 ( HH13,HH7-2,HU-PP-1,OV-1,PRL-2,PRL2,PTP4A,PTPCAAX2,ptp-IV1a,ptp-IV1b )
Gene Full Name: protein tyrosine phosphatase type IVA, member 2
Band: 1p35.2
Quick LinksEntrez ID:8073; OMIM: 601584; Uniprot ID:TP4A2_HUMAN; ENSEMBL ID: ENSG00000184007; HGNC ID: 9635
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
164Cysteine methyl ester (Probable).
Location(AA) Modifications Resource
164S-farnesyl cysteine.Swiss-Prot 53.0
Location(AA) Modification Resource
21N-linkedHMM predict
24N-linkedHMM predict
28N-linkedHMM predict
156MethylarginineHMM predict
157PhenylalanineHMM predict
158PhenylalanineHMM predict
160PhenylalanineHMM predict
164S-farnesylHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_080391
  • Location:chr1 32146379-32176574
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 32194261 32194501 240 17807
CTCF CD4SISSRdata 32194261 32194501 240 17807
CTCF G2GSE9613 32176438 32176930 492 110
CTCF G2GSE9613 32178041 32178350 309 1621
ER MCF7GSE19013 32176363 32177173 810 194
Gata2 K562GSE18868 32194157 32194895 738 17952
H3ac HepG2E 32177614 32178697 1083 1581
H3ac HepG2E 32180551 32180726 175 4064
Myc K562GSE19551 32192605 32193342 737 16399
NFkBII GM10847GSE19485 32193690 32195001 1311 17771
NFkBII GM12878GSE19485 32192780 32195056 2276 17344
NFkBII GM12892GSE19485 32193687 32195053 1366 17796
NFkBII GM15510GSE19485 32193693 32194827 1134 17686
P300 T30-glioblastomaGSE21026 32192623 32193498 875 16486
Pol2 GM12878GSE19551 32182190 32183084 894 6063
PolII HeLaGSE12783 32192364 32193961 1597 16588
PolII HeLaGSE12783 32194066 32194978 912 17948
Rb SenescentGSE19898 32176489 32176768 279 54
TAF k562GSE8489 32177614 32177847 233 1156
TAF k562GSE8489 32180551 32180997 446 4200
TAF k562GSE8489 32182331 32182568 237 5875
TFAP2C MCF7GSE21234 32176633 32177136 503 310
hScc1 BcellGSE12603 32176438 32177044 606 167
hScc1 BcellGSE12603 32177847 32178697 850 1698
hScc1 BcellGSE12603 32195873 32196370 497 19547
hScc1 CdLSGSE12603 32177929 32178631 702 1706
hScc1 CdLSGSE12603 32194177 32194719 542 17874
hScc1 CdLSGSE12603 32195873 32196370 497 19547
p130 SenescentGSE19898 32176701 32176949 248 251
p130 SenescentGSE19898 32192709 32193364 655 16462
p130 shRbQuiescentGSE19898 32192723 32193408 685 16491
p130 shRbSenescentGSE19898 32176615 32176941 326 204
p130 shRbSenescentGSE19898 32192882 32193289 407 16511
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 32145663 32145844 181 626
STAT1 HeLaGSE12783 32135062 32136970 1908 10364
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FOXA1 MCF7GSE15244 32170496 32171163 667 0
H3K4me2 HCT116GSE10453 32174694 32175767 1073 0
H3K4me3 colorectalcancer 32174694 32175691 997 0
H3ac HepG2E 32172471 32172783 312 0
H3ac HepG2E 32173062 32173643 581 0
H3ac HepG2E 32174694 32175767 1073 0
NRSF mAbJurkat 32164712 32165323 611 0
RARA MCF7GSE15244 32149155 32149505 350 0
RARA MCF7GSE15244 32170496 32171163 667 0
Rb SenescentGSE19898 32175662 32176055 393 0
TAF HelaGSE8489 32174694 32175691 997 0
TAF k562GSE8489 32172783 32173643 860 0
TAF k562GSE8489 32174694 32175767 1073 0
TFAP2C MCF7GSE21234 32149152 32149690 538 0
hScc1 BcellGSE12603 32173382 32173643 261 0
hScc1 BcellGSE12603 32175515 32175767 252 0
hScc1 CdLSGSE12603 32175431 32175767 336 0
p130 QuiescentGSE19898 32175522 32176109 587 0
p130 SenescentGSE19898 32175240 32175443 203 0
p130 shRbQuiescentGSE19898 32175439 32175992 553 0
p130 shRbSenescentGSE19898 32175898 32176120 222 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018