AutismKB 2.0

Annotation Detail for ST8SIA2


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Basic Information Top
Gene Symbol:ST8SIA2 ( HsT19690,MGC116854,MGC116857,SIAT8B,ST8SIA-II,STX )
Gene Full Name: ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
Band: 15q26.1
Quick LinksEntrez ID:8128; OMIM: 602546; Uniprot ID:SIA8B_HUMAN; ENSEMBL ID: ENSG00000140557; HGNC ID: 10870
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
60N-linked (GlcNAc...) (Potential).
72N-linked (GlcNAc...) (Potential).
89N-linked (GlcNAc...) (Potential).
134N-linked (GlcNAc...) (Potential).
219N-linked (GlcNAc...) (Potential).
234N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
60N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
72N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
89N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
134N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
219N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
234N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
26Phosphoserine(CK2)HMM predict
40Phosphothreonine(PKC)HMM predict
60N-linkedHMM predict
64Phosphoserine(CDK)HMM predict
64Phosphoserine(CDC2)HMM predict
89N-linkedHMM predict
91Phosphothreonine(PKA)HMM predict
125SulfotyrosineHMM predict
147Phosphoserine(CDC2)HMM predict
147Phosphoserine(CDK)HMM predict
206N-linkedHMM predict
219N-linkedHMM predict
232Phosphoserine(CK1)HMM predict
294Phosphothreonine(PKA)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_006011
  • Location:chr15 90738143-90812959
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 90727883 90728018 135 10193
CTCF CD4SISSRdata 90727883 90728018 135 10193
CTCF G2GSE9613 90727651 90728146 495 10245
CTCF G2GSE9613 90735504 90736299 795 2242
CTCF G2GSE9613 90737467 90738396 929 212
H3K27me3 colorectalcancer 90732266 90732583 317 5719
H3K27me3 colorectalcancer 90735294 90736046 752 2474
hScc1 BcellGSE12603 90737284 90738493 1209 255
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 90738916 90739141 225 0
CTCF G2GSE9613 90770628 90770823 195 0
H3K27me3 colorectalcancer 90739704 90740655 951 0
TFAP2C MCF7GSE21234 90743229 90743551 322 0
hScc1 BcellGSE12603 90770628 90770823 195 0
hScc1 BcellGSE12603 90779755 90780038 283 0
hScc1 BcellGSE12603 90782499 90782888 389 0
hScc1 BcellGSE12603 90811593 90812137 544 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018