AutismKB 2.0

Annotation Detail for CAMK2A


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Basic Information Top
Gene Symbol:CAMK2A ( CAMKA,KIAA0968 )
Gene Full Name: calcium/calmodulin-dependent protein kinase II alpha
Band: 5q32
Quick LinksEntrez ID:815; OMIM: 114078; Uniprot ID:KCC2A_HUMAN; ENSEMBL ID: ENSG00000070808; HGNC ID: 1460
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
13Phosphotyrosine (By similarity).
25Phosphoserine (By similarity).
275Phosphoserine (By similarity).
286Phosphothreonine; by autocatalysis (By
333Phosphoserine (By similarity).
334Phosphothreonine (By similarity).
337Phosphothreonine (By similarity).
Location(AA) Modifications Resource
25Phosphoserine (By similarity).Swiss-Prot 53.0
275Phosphoserine (By similarity).Swiss-Prot 53.0
286Phosphothreonine (by autocatalysis) (Bysimilarity).Swiss-Prot 53.0
286Phosphothreonine (CaM-KIIalpha)Phospho.ELM 6.0
333Phosphoserine (By similarity).Swiss-Prot 53.0
334Phosphothreonine (By similarity).Swiss-Prot 53.0
337Phosphothreonine (By similarity).Swiss-Prot 53.0
Location(AA) Modification Resource
10Phosphothreonine(PKA)HMM predict
78Phosphoserine(CK2)HMM predict
80Phosphoserine(CK1)HMM predict
107Phosphotyrosine(Syk)HMM predict
179Phosphotyrosine(Jak)HMM predict
179Phosphotyrosine(INSR)HMM predict
181Phosphoserine(CDC2)HMM predict
241Phosphothreonine(CDC2)HMM predict
255N-linkedHMM predict
286Phosphothreonine(PKC)HMM predict
314Phosphoserine(CAMK2)HMM predict
331Phosphoserine(CK1)HMM predict
333Phosphoserine(CK1)HMM predict
333Phosphoserine(IKK)HMM predict
335N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_015981
  • Location:chr5 149579247-149649528
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 149651775 149652058 283 2388
Myc K562GSE19551 149652802 149653389 587 3567
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 149577958 149578189 231 1174
CTCF CD4SISSRdata 149577958 149578189 231 1174
CTCF HelaGSE12889 149577994 149578340 346 1081
CTCF JurkatGSE12889 149577999 149578250 251 1123
CTCF G2GSE9613 149576517 149576953 436 2513
CTCF G2GSE9613 149577868 149578255 387 1186
hScc1 BcellGSE12603 149577760 149578351 591 1192
hScc1 CdLSGSE12603 149577732 149578377 645 1193
hScc1 G2GSE9613 149577655 149578351 696 1245
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 149579776 149580066 290 0
CTCF G2GSE9613 149580402 149580685 283 0
CTCF G2GSE9613 149582303 149582985 682 0
CTCF G2GSE9613 149585260 149585463 203 0
CTCF G2GSE9613 149599133 149599472 339 0
CTCF G2GSE9613 149602483 149603064 581 0
CTCF G2GSE9613 149604121 149605386 1265 0
CTCF G2GSE9613 149606675 149606908 233 0
CTCF G2GSE9613 149609616 149610106 490 0
CTCF G2GSE9613 149611641 149612007 366 0
CTCF G2GSE9613 149616045 149616613 568 0
CTCF G2GSE9613 149617608 149618098 490 0
CTCF G2GSE9613 149629454 149629695 241 0
CTCF G2GSE9613 149632374 149633010 636 0
CTCF G2GSE9613 149634577 149635056 479 0
CTCF G2GSE9613 149639506 149639686 180 0
CTCF G2GSE9613 149646248 149646837 589 0
CTCF G2GSE9613 149648285 149649836 1551 0
ER MCF7GSE19013 149621707 149622337 630 0
NRSF JurkatGSE13047 149631651 149632064 413 0
NRSF mAbJurkat 149630394 149631999 1605 0
NRSF mAbJurkat 149632374 149632583 209 0
NRSF-mono JurkatQuESTdata 149631540 149632063 523 0
NRSF-poly JurkatQuESTdata 149631713 149632022 309 0
Oct1 H2O2-HelaGSE14283 149591089 149591125 36 0
Oct1 HelaGSE14283 149591089 149591126 37 0
Rb shRbQuiescentGSE19898 149597226 149597485 259 0
TFAP2C MCF7GSE21234 149587323 149587808 485 0
hScc1 BcellGSE12603 149602703 149602893 190 0
hScc1 BcellGSE12603 149617199 149617418 219 0
hScc1 G2GSE9613 149632374 149632811 437 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
21665 mRNA SLC6A7 chr5 149549712 149570827 7404 mRNA CAMK2A chr5 149563423 149649385 Non-exonic Bidirectional (NOB) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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