AutismKB 2.0

Annotation Detail for RND2


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Basic Information Top
Gene Symbol:RND2 ( ARHN,RHO7,RhoN )
Gene Full Name: Rho family GTPase 2
Band: 17q21.31
Quick LinksEntrez ID:8153; OMIM: 601555; Uniprot ID:RND2_HUMAN; ENSEMBL ID: ENSG00000108830; HGNC ID: 18315
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
44Effector region (Potential).
224Cysteine methyl ester (By similarity).
Location(AA) Modifications Resource
224Cysteine methyl ester (By similarity).Swiss-Prot 53.0
224S-geranylgeranyl cysteine (Bysimilarity).Swiss-Prot 53.0
Location(AA) Modification Resource
43N-linkedHMM predict
68Phosphotyrosine(Jak)HMM predict
68Phosphotyrosine(Syk)HMM predict
93Phosphothreonine(PKC)HMM predict
129Phosphothreonine(PKC)HMM predict
166Phosphoserine(CK1)HMM predict
224S-farnesylHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_005440
  • Location:chr17 38430783-38437582
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 38430034 38430313 279 610
CTCF CD4SISSRdata 38430034 38430313 279 610
CTCF G2GSE9613 38430019 38430170 151 689
Rb SenescentGSE19898 38430246 38430661 415 330
hScc1 BcellGSE12603 38430019 38430281 262 634
hScc1 CdLSGSE12603 38430019 38430342 323 603
p130 QuiescentGSE19898 38430201 38430632 431 367
p130 SenescentGSE19898 38429914 38430692 778 481
p130 shRbQuiescentGSE19898 38429999 38430639 640 465
p130 shRbSenescentGSE19898 38430097 38430679 582 396
No data
No data
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018