AutismKB 2.0

Annotation Detail for TXNDC5


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Basic Information Top
Gene Symbol:TXNDC5 ( ERP46,EndoPDI,Hcc-2,MGC3178,PDIA15,UNQ364 )
Gene Full Name: thioredoxin domain containing 5 (endoplasmic reticulum)
Band: 6p24.3
Quick LinksEntrez ID:81567; OMIM: NA; Uniprot ID:TXND5_HUMAN; ENSEMBL ID: ENSG00000188428,ENSG00000239264; HGNC ID: 21073
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
432Prevents secretion from ER (Potential).
Location(AA) Modifications Resource
Location(AA) Modification Resource
89S-palmitoylHMM predict
106SulfotyrosineHMM predict
174Phosphothreonine(CDC2)HMM predict
174Phosphothreonine(MAPK)HMM predict
217S-palmitoylHMM predict
304O-linkedHMM predict
306O-linkedHMM predict
306Phosphothreonine(MAPK)HMM predict
308O-linkedHMM predict
350S-palmitoylHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_030810
  • Location:chr6 7826752-7856039
  • strand:-
No data
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 7838301 7838813 512 0
CTCF G2GSE9613 7844270 7844625 355 0
CTCF G2GSE9613 7854670 7854818 148 0
CTCF G2GSE9613 7855214 7856258 1044 0
H3K4me3 colorectalcancer 7854105 7854598 493 0
H3ac HepG2E 7854105 7855004 899 0
Oct1 HelaGSE14283 7828315 7828345 30 0
Oct1 HelaGSE14283 7851479 7851513 34 0
Oct1 HelaGSE14283 7852808 7852840 32 0
Rb SenescentGSE19898 7855175 7855409 234 0
TFAP2C MCF7GSE21234 7852414 7852891 477 0
VDR GM10861-UnstimGSE22484 7823172 7851509 28337 0
VDR GM10861-stimGSE22484 7822780 7857069 34289 0
hScc1 BcellGSE12603 7855089 7856258 1169 0
hScc1 CdLSGSE12603 7844240 7844659 419 0
hScc1 G2GSE9613 7855214 7856258 1044 0
p130 QuiescentGSE19898 7855111 7855289 178 0
p130 shRbSenescentGSE19898 7854974 7855375 401 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
22101 mRNA BMP6 chr6 7672008 7826726 245 mRNA TXNDC5 chr6 7826481 7856014Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018