AutismKB 2.0

Annotation Detail for AKAP1


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Basic Information Top
Gene Symbol:AKAP1 ( AKAP,AKAP121,AKAP149,AKAP84,D-AKAP1,MGC1807,PRKA1,SAKAP84 )
Gene Full Name: A kinase (PRKA) anchor protein 1
Band: 17q22
Quick LinksEntrez ID:8165; OMIM: 602449; Uniprot ID:AKAP1_HUMAN; ENSEMBL ID: ENSG00000121057; HGNC ID: 367
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
70Phosphothreonine.
105Phosphoserine (By similarity).
107Phosphoserine (By similarity).
151Phosphoserine.
169Phosphoserine.
429Phosphoserine.
533Phosphothreonine.
Location(AA) Modifications Resource
105Phosphoserine (By similarity).Swiss-Prot 53.0
107Phosphoserine (By similarity).Swiss-Prot 53.0
533Phosphothreonine.Swiss-Prot 53.0
533PhosphothreoninePhospho.ELM 6.0
Location(AA) Modification Resource
70Phosphothreonine(MAPK)HMM predict
73Phosphoserine(IKK)HMM predict
73O-linkedHMM predict
75O-linkedHMM predict
75O-linkedHMM predict
84Phosphothreonine(PKC)HMM predict
105Phosphoserine(PKA)HMM predict
113N-linkedHMM predict
192Phosphoserine(CK1)HMM predict
251Phosphoserine(ATM)HMM predict
262Phosphotyrosine(SRC)HMM predict
353Phosphoserine(ATM)HMM predict
429Phosphoserine(CDK)HMM predict
445Phosphoserine(CDK)HMM predict
445Phosphoserine(CDC2)HMM predict
453N-linkedHMM predict
469Phosphothreonine(MAPK)HMM predict
489O-linkedHMM predict
495Phosphoserine(ATM)HMM predict
512Phosphoserine(CK1)HMM predict
519Phosphoserine(IKK)HMM predict
519O-linkedHMM predict
523O-linkedHMM predict
526Phosphoserine(CDC2)HMM predict
526Phosphoserine(CDK)HMM predict
533Phosphothreonine(CDK)HMM predict
570Phosphoserine(ATM)HMM predict
570Phosphoserine(IKK)HMM predict
577Phosphoserine(IKK)HMM predict
679N-linkedHMM predict
682N-linkedHMM predict
684Phosphotyrosine(Syk)HMM predict
860O-linkedHMM predict
863Phosphoserine(CDC2)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_003488
  • Location:chr17 52517551-52553707
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3K4me2 HCT116GSE10453 52515818 52516260 442 1513
H3ac HepG2E 52514778 52515383 605 2471
H3ac HepG2E 52515818 52516260 442 1513
PHF8 Hs68minusFBSGSE20725 52516863 52517808 945 216
RARA MCF7GSE15244 52516876 52517224 348 502
Rb QuiescentGSE19898 52517023 52517566 543 257
Rb SenescentGSE19898 52517091 52517609 518 202
p130 QuiescentGSE19898 52517072 52517484 412 274
p130 SenescentGSE19898 52517000 52517464 464 320
p130 shRbQuiescentGSE19898 52517065 52517453 388 293
p130 shRbSenescentGSE19898 52517015 52517495 480 297
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 52563419 52563602 183 9803
CTCF CD4SISSRdata 52563419 52563602 183 9803
CTCF HelaGSE12889 52563367 52563585 218 9769
CTCF JurkatGSE12889 52563377 52563651 274 9807
CTCF G2GSE9613 52563150 52563599 449 9667
Myc K562GSE19551 52563297 52563718 421 9800
hScc1 BcellGSE12603 52563113 52563599 486 9649
hScc1 CdLSGSE12603 52563042 52563599 557 9613
hScc1 G2GSE9613 52563006 52563599 593 9595
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 52546416 52546746 330 0
CTCF CD4SISSRdata 52546416 52546746 330 0
CTCF G2GSE9613 52538490 52539348 858 0
CTCF G2GSE9613 52546522 52547030 508 0
ER Breast-CancerGSE22609 52517759 52518590 831 0
ER Breast-CancerGSE22609 52528935 52529699 764 0
ER MCF7GSE19013 52517101 52518771 1670 0
FoxA1 MCF7MACSdata 52517949 52518324 375 0
H3ac HepG2E 52518594 52521390 2796 0
H3ac HepG2E 52521977 52522726 749 0
Nanog hESGSE18292 52523011 52523219 208 0
Oct1 HelaGSE14283 52536917 52536945 28 0
PHF8 293TGSE20725 52516892 52518775 1883 0
PHF8 HeLaGSE20725 52516852 52518786 1934 0
RARA MCF7GSE15244 52538661 52538986 325 0
RARG MCF7GSE15244 52543561 52543810 249 0
Rb GrowingGSE19898 52518639 52518806 167 0
TFAP2C MCF7GSE21234 52517800 52519142 1342 0
USF1 HepG2E 52518594 52519168 574 0
hScc1 BcellGSE12603 52518064 52518426 362 0
hScc1 BcellGSE12603 52538950 52539241 291 0
hScc1 BcellGSE12603 52546340 52546948 608 0
hScc1 CdLSGSE12603 52517147 52518462 1315 0
hScc1 CdLSGSE12603 52546203 52546848 645 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
11427 mRNA AKAP1 chr17 52517619 52553608 4281 mRNA chr17 52524504 52528785 Non-exonic Bidirectional (NOB) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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