AutismKB 2.0

Annotation Detail for ADAMTS10


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Basic Information Top
Gene Symbol:ADAMTS10 ( ADAM-TS10,WMS )
Gene Full Name: ADAM metallopeptidase with thrombospondin type 1 motif, 10
Band: 19p13.2
Quick LinksEntrez ID:81794; OMIM: 608990; Uniprot ID:ATS10_HUMAN; ENSEMBL ID: ENSG00000142303; HGNC ID: 13201
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
74Phosphoserine.
90N-linked (GlcNAc...) (Potential).
222N-linked (GlcNAc...) (Potential).
323N-linked (GlcNAc...) (Potential).
740N-linked (GlcNAc...) (Potential).
795N-linked (GlcNAc...) (Potential).
892N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
64N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
196N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
297N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
714N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
769N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
866N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
12PhosphoserineHMM predict
31Phosphoserine(ATM)HMM predict
31Phosphoserine(CDC2)HMM predict
42Phosphothreonine(PKA)HMM predict
64N-linkedHMM predict
130Phosphotyrosine(Syk)HMM predict
144PhosphoserineHMM predict
144Phosphoserine(ATM)HMM predict
144Phosphoserine(IKK)HMM predict
144Phosphoserine(CDC2)HMM predict
148Phosphoserine(CK1)HMM predict
196N-linkedHMM predict
253Phosphoserine(IKK)HMM predict
297N-linkedHMM predict
303N-linkedHMM predict
349Phosphoserine(PKB)HMM predict
351Phosphoserine(ATM)HMM predict
475S-palmitoylHMM predict
524C-linkedHMM predict
527C-linkedHMM predict
528Phosphothreonine(CDC2)HMM predict
530C-linkedHMM predict
550Phosphoserine(CDC2)HMM predict
636Phosphothreonine(CDC2)HMM predict
677Phosphoserine(IKK)HMM predict
687Phosphoserine(CDC2)HMM predict
690Phosphoserine(MAPK)HMM predict
737Phosphothreonine(CDC2)HMM predict
797Phosphoserine(PKG)HMM predict
866N-linkedHMM predict
867C-linkedHMM predict
890Phosphoserine(PKA)HMM predict
890Phosphoserine(PKB)HMM predict
890Phosphoserine(PKG)HMM predict
928Phosphoserine(IKK)HMM predict
1033Phosphoserine(CDC2)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_030957
  • Location:chr19 8551125-8581587
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 8586642 8586936 294 5202
CTCF CD4SISSRdata 8586642 8586936 294 5202
CTCF HelaGSE12889 8586614 8586914 300 5177
p130 SenescentGSE19898 8582627 8582885 258 1169
p130 SenescentGSE19898 8583117 8583274 157 1608
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 8549489 8550143 654 1310
hScc1 CdLSGSE12603 8549339 8550143 804 1385
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 8556865 8557062 197 0
CTCF CD4SISSRdata 8556865 8557062 197 0
CTCF HelaGSE12889 8556776 8557118 342 0
CTCF JurkatGSE12889 8556809 8557194 385 0
CTCF G2GSE9613 8551700 8551972 272 0
CTCF G2GSE9613 8563256 8563420 164 0
CTCF G2GSE9613 8580171 8580751 580 0
NRSF JurkatGSE13047 8555123 8555578 455 0
NRSF mAbJurkat 8555487 8555674 187 0
P300 T30-glioblastomaGSE21026 8552947 8553719 772 0
Rb GrowingGSE19898 8563398 8563615 217 0
Rb QuiescentGSE19898 8563017 8563365 348 0
Rb QuiescentGSE19898 8563394 8563650 256 0
Rb SenescentGSE19898 8563155 8563649 494 0
hScc1 BcellGSE12603 8579483 8580751 1268 0
hScc1 G2GSE9613 8551778 8551972 194 0
p130 QuiescentGSE19898 8563143 8563333 190 0
p130 QuiescentGSE19898 8580665 8581004 339 0
p130 SenescentGSE19898 8562976 8563589 613 0
p130 shRbQuiescentGSE19898 8579881 8581506 1625 0
p130 shRbSenescentGSE19898 8580970 8581148 178 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018