AutismKB 2.0

Annotation Detail for USP11


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Basic Information Top
Gene Symbol:USP11 ( UHX1 )
Gene Full Name: ubiquitin specific peptidase 11
Band: Xp11.3
Quick LinksEntrez ID:8237; OMIM: 300050; Uniprot ID:UBP11_HUMAN; ENSEMBL ID: ENSG00000102226; HGNC ID: 12609
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
245N6-acetyllysine.
948Phosphoserine.
953Phosphoserine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
22Phosphothreonine(PKC)HMM predict
90N-linkedHMM predict
112Phosphotyrosine(INSR)HMM predict
169Phosphothreonine(PKC)HMM predict
253Phosphoserine(CK2)HMM predict
312O-linkedHMM predict
358Phosphoserine(ATM)HMM predict
407N-linkedHMM predict
430N-linkedHMM predict
561N-linkedHMM predict
562N-linkedHMM predict
564Phosphotyrosine(Syk)HMM predict
565SulfotyrosineHMM predict
601Phosphothreonine(PKC)HMM predict
605Phosphoserine(CK2)HMM predict
605Phosphoserine(CK2)HMM predict
632O-linkedHMM predict
644O-linkedHMM predict
682N-linkedHMM predict
689Phosphothreonine(CK2)HMM predict
690Phosphoserine(CDC2)HMM predict
713Phosphotyrosine(Syk)HMM predict
713Phosphotyrosine(EGFR)HMM predict
721Phosphotyrosine(INSR)HMM predict
789Phosphoserine(PKA)HMM predict
820N-linkedHMM predict
823N-linkedHMM predict
867Phosphoserine(CDC2)HMM predict
895Phosphoserine(CAMK2)HMM predict
895Phosphoserine(IKK)HMM predict
895Phosphoserine(CDC2)HMM predict
899O-linkedHMM predict
905O-linkedHMM predict
910Phosphoserine(IKK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_004651
  • Location:chrX 46977257-46992669
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
TFAP2C MCF7GSE21234 46976653 46977237 584 313
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 46993357 46993792 435 905
Fos K562GSE19551 47008999 47009514 515 16587
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 46977353 46977936 583 0
CTCF G2GSE9613 46985074 46985355 281 0
ER Fulvestrant-MCF7GSE14664 46983356 46983389 33 0
ETS1 JurkatGSE17954 46976890 46978471 1581 0
FOXA1 MCF7GSE15244 46977678 46978135 457 0
H3ac HepG2E 46977642 46978349 707 0
Rb shRbSenescenceGSE19898 46977459 46977665 206 0
TAF HelaGSE8489 46978096 46978449 353 0
TAF k562GSE8489 46978135 46978449 314 0
TFAP2C MCF7GSE21234 46977661 46978229 568 0
hScc1 G2GSE9613 46977608 46977972 364 0
hScc1 G2GSE9613 46985025 46985663 638 0
hScc1 G2GSE9613 46985900 46986594 694 0
hScc1 G2GSE9613 46988397 46989150 753 0
p130 QuiescentGSE19898 46977920 46978278 358 0
p130 SenescentGSE19898 46977971 46978499 528 0
p130 shRbQuiescentGSE19898 46977087 46977661 574 0
p130 shRbQuiescentGSE19898 46977736 46978126 390 0
p130 shRbSenescentGSE19898 46977892 46978330 438 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018