AutismKB 2.0

Annotation Detail for CDC7


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:CDC7 ( CDC7L1,HsCDC7,Hsk1,MGC117361,MGC126237,MGC126238,huCDC7 )
Gene Full Name: cell division cycle 7 homolog (S. cerevisiae)
Band: 1p22.1
Quick LinksEntrez ID:8317; OMIM: 603311; Uniprot ID:CDC7_HUMAN; ENSEMBL ID: ENSG00000097046; HGNC ID: 1745
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
16Phosphoserine.
27Phosphoserine.
503Phosphothreonine.
508Phosphotyrosine.
509Phosphoserine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
16Phosphoserine(CDK)HMM predict
16Phosphoserine(CDC2)HMM predict
141Phosphoserine(CK2)HMM predict
224Phosphoserine(ATM)HMM predict
226N-linkedHMM predict
239Phosphoserine(ATM)HMM predict
251Phosphothreonine(PKC)HMM predict
311Phosphoserine(PKG)HMM predict
323Phosphothreonine(PKC)HMM predict
344O-linkedHMM predict
363S-palmitoylHMM predict
390N-linkedHMM predict
503Phosphothreonine(CDK)HMM predict
543Phosphotyrosine(Syk)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_003503
  • Location:chr1 91739031-91763900
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Oct1 H2O2-HelaGSE14283 91736268 91736294 26 2751
Oct1 HelaGSE14283 91719862 91719938 76 19132
Oct1 HelaGSE14283 91736260 91736295 35 2754
TAF HelaGSE8489 91737934 91739648 1714 241
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Myc K562GSE19551 91768078 91768404 326 4341
Oct1 HelaGSE14283 91770472 91770516 44 6594
Rb QuiescentGSE19898 91771591 91771731 140 7761
hScc1 CdLSGSE12603 91767842 91768590 748 4316
hScc1 G2GSE9613 91768050 91768766 716 4508
p63 keratinocytesGSE17611 91767618 91768887 1269 4352
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 91739351 91739761 410 0
E2F4 G0GSE7516 91738831 91739422 591 0
ER E2-MCF7GSE14664 91741890 91741922 32 0
ER E2-MCF7GSE14664 91760287 91760319 32 0
HIF1 NormHepG2 91738726 91739422 696 0
LIN9 G0GSE7516 91738831 91739351 520 0
PHF8 HeLaGSE20725 91738532 91739874 1342 0
Rb GrowingGSE19898 91738744 91739419 675 0
Rb QuiescentGSE19898 91738681 91739452 771 0
Rb SenescentGSE19898 91738642 91739680 1038 0
Rb shRbSenescenceGSE19898 91738693 91739395 702 0
TAF k562GSE8489 91737734 91740852 3118 0
TFAP2C MCF7GSE21234 91738879 91739585 706 0
hScc1 BcellGSE12603 91739241 91739728 487 0
hScc1 BcellGSE12603 91749530 91749849 319 0
hScc1 CdLSGSE12603 91740852 91741408 556 0
hScc1 CdLSGSE12603 91749430 91750079 649 0
hScc1 CdLSGSE12603 91751104 91751565 461 0
p130 QuiescentGSE19898 91738716 91739562 846 0
p130 SenescentGSE19898 91738538 91739710 1172 0
p130 shRbQuiescentGSE19898 91738543 91739577 1034 0
p130 shRbSenescentGSE19898 91738658 91739617 959 0
p130 G0GSE7516 91738831 91739952 1121 0
p130 SGSE7516 91738586 91739683 1097 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-1296 hsa-mir-1296 10 20332239
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018