AutismKB 2.0

Annotation Detail for CDC45


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Basic Information Top
Gene Symbol:CDC45 ( CDC45L,CDC45L2,PORC-PI-1 )
Gene Full Name: cell division cycle 45 homolog (S. cerevisiae)
Band: 22q11.21
Quick LinksEntrez ID:8318; OMIM: 603465; Uniprot ID:CDC45_HUMAN; ENSEMBL ID: ENSG00000093009; HGNC ID: 1739
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
130Phosphotyrosine.
144Phosphoserine.
148Phosphoserine.
151Phosphoserine.
Location(AA) Modifications Resource
No data
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_003504
  • Location:chr22 17847415-17888133
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FOXA1 MCF7GSE15244 17846838 17847676 838 159
RARA MCF7GSE15244 17846896 17847356 460 290
Rb SenescentGSE19898 17846896 17847613 717 161
p130 SenescentGSE19898 17846693 17848005 1312 67
p130 shRbSenescentGSE19898 17846523 17848098 1575 105
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 17863474 17863720 246 0
CTCF CD4SISSRdata 17863474 17863720 246 0
E2F4 G0GSE7516 17846711 17848622 1911 0
LIN54 G0GSE7516 17846632 17848486 1854 0
LIN9 G0GSE7516 17846438 17848800 2362 0
LIN9 SGSE7516 17846711 17848486 1775 0
PHF8 HeLaGSE20725 17847040 17847913 873 0
Rb GrowingGSE19898 17847348 17847604 256 0
Rb QuiescentGSE19898 17847211 17847688 477 0
TAF k562GSE8489 17848069 17848834 765 0
TFAP2C MCF7GSE21234 17864745 17865309 564 0
p130 QuiescentGSE19898 17847210 17847892 682 0
p130 shRbQuiescentGSE19898 17846928 17847906 978 0
p130 shRbQuiescentGSE19898 17872672 17873154 482 0
p130 G0GSE7516 17846554 17848800 2246 0
p130 SGSE7516 17846438 17848486 2048 0
p63 keratinocytesGSE17611 17878035 17879094 1059 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
17142 mRNA CDC45L chr22 17841969 17882688 144 EST chr22 17845645 17847978Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018