AutismKB 2.0

Annotation Detail for FZD1


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Basic Information Top
Gene Symbol:FZD1 ( DKFZp564G072,FLJ95923 )
Gene Full Name: frizzled homolog 1 (Drosophila)
Band: 7q21.13
Quick LinksEntrez ID:8321; OMIM: 603408; Uniprot ID:FZD1_HUMAN; ENSEMBL ID: ENSG00000157240; HGNC ID: 4038
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
130N-linked (GlcNAc...) (Potential).
231N-linked (GlcNAc...) (Potential).
630Lys-Thr-X-X-X-Trp motif, mediates
647PDZ-binding.
Location(AA) Modifications Resource
130N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
231N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
109Phosphoserine(ATM)HMM predict
109Phosphoserine(PKB)HMM predict
130N-linkedHMM predict
136N-linkedHMM predict
187S-palmitoylHMM predict
231N-linkedHMM predict
237Phosphothreonine(MAPK)HMM predict
239Phosphothreonine(CDK)HMM predict
239Phosphothreonine(MAPK)HMM predict
306Phosphotyrosine(SRC)HMM predict
397Phosphothreonine(PKC)HMM predict
545O-linkedHMM predict
597O-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_003505
  • Location:chr7 90731718-90736066
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3K4me3 colorectalcancer 90730608 90731321 713 754
TFAP2C MCF7GSE21234 90716928 90717584 656 14463
hScc1 BcellGSE12603 90731282 90731593 311 281
hScc1 CdLSGSE12603 90730996 90731752 756 345
hScc1 G2GSE9613 90730797 90732467 1670 87
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 90755476 90756047 571 19695
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T30-glioblastomaGSE21026 90731160 90732889 1729 0
CTCF G2GSE9613 90731525 90732541 1016 0
CTCF G2GSE9613 90732847 90733376 529 0
ER E2-MCF7GSE14664 90733232 90733268 36 0
hScc1 BcellGSE12603 90732040 90732875 835 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018