AutismKB 2.0

Annotation Detail for FZD8


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Basic Information Top
Gene Symbol:FZD8 ( FZ-8,hFZ8 )
Gene Full Name: frizzled homolog 8 (Drosophila)
Band: 10p11.21
Quick LinksEntrez ID:8325; OMIM: 606146; Uniprot ID:FZD8_HUMAN; ENSEMBL ID: ENSG00000177283; HGNC ID: 4046
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
49N-linked (GlcNAc...) (Potential).
152N-linked (GlcNAc...) (Potential).
475N-linked (GlcNAc...) (Potential).
613Lys-Thr-X-X-X-Trp motif, mediates
694PDZ-binding.
Location(AA) Modifications Resource
49N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
152N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
475N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
49N-linkedHMM predict
52Phosphotyrosine(INSR)HMM predict
55N-linkedHMM predict
152N-linkedHMM predict
157O-linkedHMM predict
162PhosphoserineHMM predict
162Phosphoserine(CDK)HMM predict
162Phosphoserine(MAPK)HMM predict
178O-linkedHMM predict
193MethylarginineHMM predict
197MethylarginineHMM predict
210MethylarginineHMM predict
277Phosphothreonine(PKC)HMM predict
376Phosphotyrosine(INSR)HMM predict
620S-palmitoylHMM predict
621S-palmitoylHMM predict
666Phosphotyrosine(INSR)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_031866
  • Location:chr10 35967182-35970367
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Nanog hESGSE18292 35986603 35987015 412 16442
Rb QuiescentGSE19898 35971522 35971656 134 1222
Rb SenescentGSE19898 35971017 35971463 446 873
hScc1 BcellGSE12603 35971608 35972455 847 1664
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 35964410 35964875 465 2540
CTCF CD4SISSRdata 35964410 35964875 465 2540
hScc1 BcellGSE12603 35963891 35964991 1100 2742
hScc1 CdLSGSE12603 35964101 35964991 890 2637
hScc1 G2GSE9613 35964395 35964991 596 2490
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
hScc1 BcellGSE12603 35968658 35971168 2510 0
hScc1 CdLSGSE12603 35969371 35971132 1761 0
hScc1 G2GSE9613 35968487 35971197 2710 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018