AutismKB 2.0

Annotation Detail for TCF7L1


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Basic Information Top
Gene Symbol:TCF7L1 ( TCF-3,TCF3 )
Gene Full Name: transcription factor 7-like 1 (T-cell specific, HMG-box)
Band: 2p11.2
Quick LinksEntrez ID:83439; OMIM: 604652; Uniprot ID:TF7L1_HUMAN; ENSEMBL ID: ENSG00000152284; HGNC ID: 11640
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
427Nuclear localization signal (Potential).
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_031283
  • Location:chr2 85214244-85391014
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 85213549 85213701 152 620
CTCF CD4SISSRdata 85213549 85213701 152 620
Nanog ESGSE20650 85200421 85201072 651 13498
Nanog hESGSE18292 85200571 85200942 371 13488
Oct4 hESGSE21916 85200465 85201046 581 13489
hScc1 BcellGSE12603 85213499 85214785 1286 103
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018