AutismKB 2.0

Annotation Detail for PUS3


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Basic Information Top
Gene Symbol:PUS3 ( 2610020J05Rik,FLJ23638 )
Gene Full Name: pseudouridylate synthase 3
Band: 11q24.2
Quick LinksEntrez ID:83480; OMIM: NA; Uniprot ID:PUS3_HUMAN; ENSEMBL ID: ENSG00000110060; HGNC ID: 25461
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
2N-acetylalanine.
456Phosphothreonine.
466Phosphothreonine.
468Phosphothreonine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
9N-linkedHMM predict
81Phosphoserine(CK2)HMM predict
86N-linkedHMM predict
87N-linkedHMM predict
344N-linkedHMM predict
388C-linkedHMM predict
454N-linkedHMM predict
466Phosphothreonine(MAPK)HMM predict
466Phosphothreonine(CDK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_031307
  • Location:chr11 125268590-125278314
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ETS1 JurkatGSE17954 125277855 125279416 1561 321
NRSF mAbJurkat 125277724 125279530 1806 313
NRSF pAbJurkat 125277999 125279640 1641 505
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3K4me2 HCT116GSE10453 125277033 125277392 359 0
H3K4me3 colorectalcancer 125276963 125277392 429 0
H3K4me3 colorectalcancer 125277724 125278296 572 0
H3ac HepG2E 125276850 125277392 542 0
P300 T30-glioblastomaGSE21026 125277728 125278840 1112 0
STAT1 HeLaGSE12782 125277432 125278942 1510 0
STAT1 HeLaGSE12783 125277480 125278918 1438 0
STAT1 IFNSISSRdata 125277680 125278765 1085 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
5391 mRNA HYLS1 chr11 125258718 125275749 7159 mRNA PUS3 chr11 125268590 125278315 Non-exonic Bidirectional (NOB) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018