Annotation Detail for HIST2H2BE
Basic Information
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| Gene Symbol: | HIST2H2BE ( GL105,H2B,H2B.1,H2BFQ,H2BGL105,H2BQ,MGC119802,MGC119804,MGC129733,MGC129734 ) |
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| Gene Full Name: | histone cluster 2, H2be |
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| Band: | 1q21.2 |
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| Quick Links | Entrez ID:8349; OMIM: 601831; Uniprot ID:H2B2E_HUMAN; ENSEMBL ID: ENSG00000184678; HGNC ID: 4760 |
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| Relate to Another Database: |
SFARIGene;
denovo-db |
| Location(AA) |
Modification |
|---|
| 6 | N6-acetyllysine. |
| 12 | N6-acetyllysine. |
| 13 | N6-acetyllysine. |
| 15 | Phosphoserine; by STK4. |
| 16 | N6-acetyllysine. |
| 17 | N6-acetyllysine. |
| 21 | N6-acetyllysine. |
| 24 | N6-acetyllysine. |
| 47 | N6-methyllysine. |
| 58 | N6,N6-dimethyllysine. |
| 109 | N6-acetyllysine; alternate. |
| 109 | N6-methyllysine; alternate. |
| Location(AA) |
Modifications |
Resource |
| 6 | N6-acetyllysine. | Swiss-Prot 53.0 |
| 12 | N6-acetyllysine. | Swiss-Prot 53.0 |
| 13 | N6-acetyllysine. | Swiss-Prot 53.0 |
| 15 | Phosphoserine (by STK4). | Swiss-Prot 53.0 |
| 16 | N6-acetyllysine. | Swiss-Prot 53.0 |
| 17 | N6-acetyllysine. | Swiss-Prot 53.0 |
| 21 | N6-acetyllysine. | Swiss-Prot 53.0 |
| 24 | N6-acetyllysine. | Swiss-Prot 53.0 |
| 47 | N6-methyllysine. | Swiss-Prot 53.0 |
| 58 | N6,N6-dimethyllysine. | Swiss-Prot 53.0 |
| 109 | N6-acetyllysine; alternate. | Swiss-Prot 53.0 |
| 109 | N6-methyllysine; alternate. | Swiss-Prot 53.0 |
| 121 | Glycyl lysine isopeptide (Lys-Gly)(interchain with G-Cter in ubiquitin). | Swiss-Prot 53.0 |
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
- RefSeq ID: NM_003528
- Location:chr1 148122635-148124855
- strand:-
| Transcrip Factors |
Experimental Cell |
Database |
TF Binding Start |
TF Binding End |
TF Binding Length |
The Distance to Gene |
|---|
| PolII |
HeLa | GSE12783 | 148121387 |
148128485 |
7098 |
81 |
| VDR |
GM10855-stim | GSE22484 | 148122085 |
148127760 |
5675 |
67 |
| Transcrip Factors |
Experimental Cell |
Database |
TF Binding Start |
TF Binding End |
TF Binding Length |
The Distance to Gene |
|---|
| CTCF |
G2 | GSE9613 | 148123947 |
148124082 |
135 |
0 |
| E2F4 |
G0 | GSE7516 | 148122798 |
148124819 |
2021 |
0 |
| FOXA1 |
MCF7 | GSE15244 | 148122866 |
148125586 |
2720 |
0 |
| H3K4me2 |
HCT116 | GSE10453 | 148123278 |
148123770 |
492 |
0 |
| H3K4me3 |
colorectal | cancer | 148123085 |
148123694 |
609 |
0 |
| H3K4me3 |
colorectal | cancer | 148124058 |
148124819 |
761 |
0 |
| H3ac |
HepG2 | E | 148123313 |
148124862 |
1549 |
0 |
| LIN54 |
G0 | GSE7516 | 148123626 |
148124224 |
598 |
0 |
| LIN9 |
G0 | GSE7516 | 148122866 |
148126252 |
3386 |
0 |
| LIN9 |
S | GSE7516 | 148123085 |
148124819 |
1734 |
0 |
| PHF8 |
293T | GSE20725 | 148123679 |
148125640 |
1961 |
0 |
| RARA |
MCF7 | GSE15244 | 148122762 |
148125622 |
2860 |
0 |
| RARG |
MCF7 | GSE15244 | 148123085 |
148125586 |
2501 |
0 |
| Rb |
Growing | GSE19898 | 148124170 |
148124404 |
234 |
0 |
| TAF |
k562 | GSE8489 | 148122609 |
148125586 |
2977 |
0 |
| VDR |
GM10855-Unstim | GSE22484 | 148122124 |
148127515 |
5391 |
0 |
| VDR |
GM10861-stim | GSE22484 | 148121709 |
148127825 |
6116 |
0 |
| p130 |
Quiescent | GSE19898 | 148123365 |
148124181 |
816 |
0 |
| p130 |
Senescent | GSE19898 | 148123296 |
148124457 |
1161 |
0 |
| p130 |
shRbQuiescent | GSE19898 | 148122493 |
148122965 |
472 |
0 |
| p130 |
shRbQuiescent | GSE19898 | 148123070 |
148124296 |
1226 |
0 |
| p130 |
shRbSenescent | GSE19898 | 148123033 |
148124376 |
1343 |
0 |
| p130 |
G0 | GSE7516 | 148122762 |
148125586 |
2824 |
0 |
| p130 |
S | GSE7516 | 148123347 |
148124153 |
806 |
0 |
Validated miRNA targets