AutismKB 2.0

Annotation Detail for CASP2


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Basic Information Top
Gene Symbol:CASP2 ( CASP-2,ICH-1L,ICH-1L/1S,ICH1,NEDD2 )
Gene Full Name: caspase 2, apoptosis-related cysteine peptidase
Band: 7q34
Quick LinksEntrez ID:835; OMIM: 600639; Uniprot ID:CASP2_HUMAN; ENSEMBL ID: ENSG00000106144; HGNC ID: 1503
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
2N-acetylalanine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
82Phosphoserine(ATM)HMM predict
136SulfotyrosineHMM predict
267Phosphothreonine(PKA)HMM predict
420Phosphotyrosine(INSR)HMM predict
420Phosphotyrosine(Syk)HMM predict
437SerineHMM predict
440S-palmitoylHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_032983
  • Location:chr7 142695523-142714905
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 142695070 142695843 773 67
Rb QuiescentGSE19898 142695135 142695825 690 44
Rb SenescentGSE19898 142695122 142695855 733 35
hScc1 BcellGSE12603 142695070 142695880 810 49
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 142707047 142707366 319 0
CTCF CD4GSE12889 142712668 142713025 357 0
CTCF CD4SISSRdata 142707047 142707366 319 0
CTCF CD4SISSRdata 142712668 142713025 357 0
CTCF JurkatGSE12889 142712766 142712954 188 0
CTCF G2GSE9613 142706902 142707637 735 0
CTCF G2GSE9613 142710927 142711139 212 0
CTCF G2GSE9613 142712123 142713174 1051 0
FOXA1 MCF7GSE15244 142707806 142709174 1368 0
FoxA1 MCF7MACSdata 142708239 142708776 537 0
H3ac HepG2E 142696140 142697206 1066 0
PHF8 293TGSE20725 142695229 142696305 1076 0
PHF8 HeLaGSE20725 142695124 142696102 978 0
RARA MCF7GSE15244 142708042 142708883 841 0
Rb GrowingGSE19898 142695580 142695802 222 0
Rb shRbQuiescentGSE19898 142695443 142695833 390 0
TAF HelaGSE8489 142696319 142696782 463 0
hScc1 BcellGSE12603 142712670 142713139 469 0
hScc1 CdLSGSE12603 142695070 142696068 998 0
hScc1 CdLSGSE12603 142712601 142713031 430 0
hScc1 G2GSE9613 142712601 142713174 573 0
p130 QuiescentGSE19898 142695551 142695936 385 0
p130 SenescentGSE19898 142695049 142696038 989 0
p130 shRbSenescentGSE19898 142695123 142695949 826 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018