AutismKB 2.0

Annotation Detail for GRWD1


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Basic Information Top
Gene Symbol:GRWD1 ( CDW4,GRWD,KIAA1942,RRB1,WDR28 )
Gene Full Name: glutamate-rich WD repeat containing 1
Band: 19q13.33
Quick LinksEntrez ID:83743; OMIM: 610597; Uniprot ID:GRWD1_HUMAN; ENSEMBL ID: ENSG00000105447; HGNC ID: 21270
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
10Phosphothreonine.
119Phosphoserine.
122Phosphoserine.
344Phosphoserine.
Location(AA) Modifications Resource
119Phosphoserine.Swiss-Prot 53.0
122Phosphoserine.Swiss-Prot 53.0
Location(AA) Modification Resource
10Phosphothreonine(PKA)HMM predict
24Phosphothreonine(CK2)HMM predict
26O-linkedHMM predict
79N-linkedHMM predict
119O-linkedHMM predict
122Phosphoserine(CK2)HMM predict
122Phosphoserine(CK1)HMM predict
122PhosphoserineHMM predict
122Phosphoserine(CK2)HMM predict
158Phosphoserine(PKG)HMM predict
275O-linkedHMM predict
344Phosphoserine(IKK)HMM predict
344Phosphoserine(CDC2)HMM predict
358Phosphoserine(CK1)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_031485
  • Location:chr19 53640873-53648965
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
p130 shRbSenescentGSE19898 53640401 53640659 258 344
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
hScc1 BcellGSE12603 53649551 53649880 329 750
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ETS1 JurkatGSE17954 53640306 53641708 1402 0
GABP k562GSE8489 53641129 53641557 428 0
H3K4me3 colorectalcancer 53640954 53641484 530 0
H3ac HepG2E 53640851 53641557 706 0
LIN9 G0GSE7516 53640815 53641557 742 0
LIN9 SGSE7516 53640920 53641522 602 0
Oct1 H2O2-HelaGSE14283 53641459 53641499 40 0
Oct1 HelaGSE14283 53641459 53641499 40 0
P300 T30-glioblastomaGSE21026 53640087 53641669 1582 0
PHF8 HeLaGSE20725 53640611 53641709 1098 0
Rb SenescentGSE19898 53640859 53641201 342 0
p130 QuiescentGSE19898 53640802 53641264 462 0
p130 QuiescentGSE19898 53641279 53641572 293 0
p130 SenescentGSE19898 53640637 53641417 780 0
p130 shRbQuiescentGSE19898 53640635 53641399 764 0
p130 shRbSenescentGSE19898 53640777 53641388 611 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018