Annotation Detail for ATAD3B

View Evidences	View Variants	View Annotations

Basic Information Top

Gene Symbol:	ATAD3B ( AAA-TOB3,KIAA1273,TOB3 )
Gene Full Name:	ATPase family, AAA domain containing 3B
Band:	1p36.33
Quick Links	Entrez ID:83858; OMIM: 612317; Uniprot ID:ATD3B_HUMAN; ENSEMBL ID: ENSG00000160072; HGNC ID: 24007
Relate to Another Database:	SFARIGene; denovo-db

Post Translation Modification

Location(AA)	Modification
135	N6-acetyllysine.
427	N6-acetyllysine.

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
ETS1	Jurkat	GSE17954	1396470	1397342	872	121
Fos	K562	GSE19551	1396378	1397183	805	246
H3K4me3	colorectal	cancer	1396671	1397315	644	34
Myc	K562	GSE19551	1396176	1397150	974	364
P300	T30-glioblastoma	GSE21026	1396330	1397318	988	203
Rb	Growing	GSE19898	1396727	1397052	325	137
Rb	Quiescent	GSE19898	1396724	1397082	358	124
Rb	Senescent	GSE19898	1396616	1397069	453	184
TAFII	hES	GSE17917	1396632	1397137	505	142
TFAP2C	MCF7	GSE21234	1396752	1397151	399	75
p130	Quiescent	GSE19898	1396735	1397042	307	138
p130	Senescent	GSE19898	1396437	1397071	634	273
p130	shRbQuiescent	GSE19898	1396739	1397054	315	130
p130	shRbSenescent	GSE19898	1396702	1397048	346	152
p130	G0	GSE7516	1396635	1397008	373	205

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
USF1	HepG2	E	1428505	1429172	667	7395
hScc1	Bcell	GSE12603	1421596	1422009	413	359

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length
CTCF	G2	GSE9613	1396878	1397518	640
CTCF	G2	GSE9613	1401303	1401677	374
CTCF	G2	GSE9613	1403878	1404402	524
CTCF	G2	GSE9613	1410151	1410552	401
CTCF	G2	GSE9613	1414349	1414721	372
CTCF	G2	GSE9613	1415151	1415440	289
CTCF	G2	GSE9613	1419844	1420463	619
H3K4me3	colorectal	cancer	1397704	1397988	284
H3ac	HepG2	E	1397554	1398043	489
H3ac	HepG2	E	1399053	1399273	220
H3ac	HepG2	E	1400058	1400478	420
PHF8	HeLa	GSE20725	1396547	1397563	1016
hScc1	Bcell	GSE12603	1396671	1397518	847
hScc1	Bcell	GSE12603	1411016	1411806	790
hScc1	Bcell	GSE12603	1415183	1416413	1230
hScc1	Bcell	GSE12603	1419716	1420931	1215

Validated miRNA targets

Micro RNA Name	Stem Loop Name	The chromosome that miRNA located	Publication
hsa-let-7b	hsa-let-7b	22	18668040
hsa-let-7b*	hsa-let-7b	22	18668040
hsa-miR-1	hsa-mir-1-2	18	18668040
hsa-miR-1	hsa-mir-1-1	20	18668040
hsa-miR-155	hsa-mir-155	21	18668040
hsa-miR-155*	hsa-mir-155	21	18668040
hsa-miR-16	hsa-mir-16-1	13	18668040
hsa-miR-16	hsa-mir-16-2	3	18668040
hsa-miR-30a	hsa-mir-30a	6	18668040
hsa-miR-30a*	hsa-mir-30a	6	18668040
hsa-miR-30b	hsa-mir-30b	8	18668040
hsa-miR-30b*	hsa-mir-30b	8	18668040
hsa-miR-30c	hsa-mir-30c-2	6	18668040
hsa-miR-30c	hsa-mir-30c-1	1	18668040
hsa-miR-30c-1*	hsa-mir-30c-1	1	18668040
hsa-miR-30c-2*	hsa-mir-30c-2	6	18668040
hsa-miR-30d	hsa-mir-30d	8	18668040
hsa-miR-30d*	hsa-mir-30d	8	18668040
hsa-miR-30e	hsa-mir-30e	1	18668040
hsa-miR-30e*	hsa-mir-30e	1	18668040

ID in Tarbase	Data Type	Support Type	miRNA	Gene	Direct Support	Publication
833	Unknown	pSILAC	let-7b	ATAD3B	down 50-25%	18668040
911	Unknown	pSILAC	LNA_let-7b	ATAD3B	up 25-50%	18668040
Ensembl	Protein Type	Differentially expressed in	Pathology or Event	Mis Regulation	Gene Expression	Tumour Involvement
ENSG00000160072		n_a	n_a	n_a	"lymphocyte, muscle cell, epithelium"	"malignant tumour, carcinoma, benign tumour, non-Hodgkin's, sarcoma"
ENSG00000160072		n_a	n_a	n_a	"lymphocyte, muscle cell, epithelium"	"malignant tumour, carcinoma, benign tumour, non-Hodgkin's, sarcoma"

Cis-Nats regulation

Simple Query:

Paper Collected: 6/30/2018

Last Update: 8/26/2018