AutismKB 2.0

Annotation Detail for CDCA7


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Basic Information Top
Gene Symbol:CDCA7 ( FLJ14722,FLJ14736,JPO1,MGC34109 )
Gene Full Name: cell division cycle associated 7
Band: 2q31.1
Quick LinksEntrez ID:83879; OMIM: 609937; Uniprot ID:CDCA7_HUMAN; ENSEMBL ID: ENSG00000144354; HGNC ID: 14628
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
22Phosphotyrosine(EGFR)HMM predict
37Phosphoserine(IKK)HMM predict
40Phosphoserine(IKK)HMM predict
95Phosphoserine(IKK)HMM predict
98Phosphoserine(CK1)HMM predict
98Phosphoserine(IKK)HMM predict
102Phosphoserine(IKK)HMM predict
104Phosphoserine(CK1)HMM predict
104Phosphoserine(CK2)HMM predict
106Phosphoserine(CK2)HMM predict
106Phosphoserine(CK1)HMM predict
106Phosphoserine(IKK)HMM predict
138Phosphoserine(IKK)HMM predict
163Phosphothreonine(PKA)HMM predict
169Phosphoserine(PKC)HMM predict
181Phosphothreonine(PKC)HMM predict
205Phosphotyrosine(INSR)HMM predict
205Phosphotyrosine(SRC)HMM predict
213Phosphothreonine(PKA)HMM predict
213Phosphothreonine(PKC)HMM predict
217Phosphotyrosine(INSR)HMM predict
232Phosphoserine(IKK)HMM predict
234Phosphothreonine(PKC)HMM predict
246Phosphothreonine(CK2)HMM predict
300S-palmitoylHMM predict
328N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_031942
  • Location:chr2 173927806-173941963
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
E2F4 G0GSE7516 173926833 173927954 1121 413
ER MCF7GSE19013 173925571 173925963 392 2040
FOXA1 MCF7GSE15244 173920171 173921149 978 7147
FoxA1 MCF7MACSdata 173920489 173920690 201 7217
H3K4me3 colorectalcancer 173926907 173927404 497 651
H3ac HepG2E 173926907 173927588 681 559
LIN54 G0GSE7516 173927211 173927775 564 314
LIN9 G0GSE7516 173926417 173927990 1573 603
LIN9 SGSE7516 173926969 173928181 1212 232
Rb GrowingGSE19898 173927424 173927853 429 168
Rb QuiescentGSE19898 173927277 173927895 618 221
Rb SenescentGSE19898 173927315 173928016 701 141
Rb shRbSenescenceGSE19898 173927308 173927988 680 159
p130 QuiescentGSE19898 173927092 173927878 786 322
p130 SenescentGSE19898 173927029 173927882 853 351
p130 shRbQuiescentGSE19898 173926984 173928182 1198 224
p130 shRbSenescentGSE19898 173927041 173927847 806 363
p130 G0GSE7516 173926592 173927990 1398 516
p130 SGSE7516 173927028 173928057 1029 264
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 173959562 173959746 184 17691
RNAII Tamoxifen-MCF7GSE14664 173943983 173944020 37 2038
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 173927886 173928470 584 0
ER Fulvestrant-MCF7GSE14664 173940855 173940946 91 0
H3ac HepG2E 173928841 173929359 518 0
hScc1 BcellGSE12603 173927404 173928337 933 0
p130 shRbSenescentGSE19898 173927984 173928263 279 0
p63 keratinocytesGSE17611 173928798 173929705 907 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-1 hsa-mir-1-2 18 15685193
hsa-miR-1 hsa-mir-1-1 20 15685193
hsa-miR-124 hsa-mir-124-1 8 15685193
hsa-miR-124 hsa-mir-124-2 8 15685193
hsa-miR-124 hsa-mir-124-3 20 15685193
hsa-miR-373 hsa-mir-373 19 15685193
hsa-miR-373* hsa-mir-373 19 15685193
ID in Tarbase Data Type Support Type miRNA Gene Direct Support Publication
406 Unknown MicroArray miR-124 CDCA7 n_a 15685193
Ensembl Protein Type Differentially expressed in Pathology or Event Mis Regulation Gene Expression Tumour Involvement
ENSG00000144354 G1-to-S transition n_a n_a "epithelium, squamous cell, lymphoblast, lymphocyte, muscle cell" "benign tumour, malignant tumour, carcinoma, leukaemia, non-Hodgkin's, sarcoma"
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018