AutismKB 2.0

Annotation Detail for TAGLN2


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Basic Information Top
Gene Symbol:TAGLN2 ( HA1756,KIAA0120 )
Gene Full Name: transgelin 2
Band: 1q23.2
Quick LinksEntrez ID:8407; OMIM: 604634; Uniprot ID:TAGL2_HUMAN; ENSEMBL ID: ENSG00000158710; HGNC ID: 11554
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
2N-acetylalanine.
8Phosphotyrosine.
17N6-acetyllysine.
20N6-acetyllysine.
163Phosphoserine.
185Phosphoserine.
192Phosphotyrosine.
Location(AA) Modifications Resource
2N-acetylalanine.Swiss-Prot 53.0
Location(AA) Modification Resource
49MethylarginineHMM predict
106N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_003564
  • Location:chr1 158154526-158161907
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 158161807 158162075 268 34
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 158153914 158154079 165 530
FOXA1 MCF7GSE15244 158150118 158151188 1070 3874
FOXA1 MCF7GSE15244 158152635 158153075 440 1672
FoxA1 MCF7MACSdata 158150730 158151127 397 3598
FoxA1 MCF7MACSdata 158152580 158152963 383 1755
P300 T30-glioblastomaGSE21026 158146351 158147655 1304 7524
RARA MCF7GSE15244 158152635 158153075 440 1672
TFAP2C MCF7GSE21234 158152353 158153410 1057 1645
hScc1 BcellGSE12603 158146702 158146845 143 7753
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 158154651 158155275 624 0
CTCF G2GSE9613 158159257 158159597 340 0
CTCF G2GSE9613 158160923 158161276 353 0
H3K4me3 colorectalcancer 158159667 158160455 788 0
NFkBII GM12878GSE19485 158157174 158158895 1721 0
Oct1 HelaGSE14283 158157425 158157489 64 0
Pol2 GM12878GSE19551 158157666 158162288 4622 0
Rb GrowingGSE19898 158159724 158159984 260 0
Rb GrowingGSE19898 158160111 158160260 149 0
Rb QuiescentGSE19898 158159664 158159936 272 0
Rb SenescentGSE19898 158159633 158159912 279 0
hScc1 BcellGSE12603 158160923 158161415 492 0
p130 QuiescentGSE19898 158159955 158161083 1128 0
p130 SenescentGSE19898 158159633 158160439 806 0
p130 shRbQuiescentGSE19898 158159327 158159846 519 0
p130 shRbQuiescentGSE19898 158159927 158161218 1291 0
p130 shRbSenescentGSE19898 158159939 158160895 956 0
p130 shRbSenescentGSE19898 158160903 158162102 1199 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-1 hsa-mir-1-2 18 21378409
hsa-miR-1 hsa-mir-1-1 20 21378409
hsa-miR-1 hsa-mir-1-2 18 21304530
hsa-miR-1 hsa-mir-1-1 20 21304530
hsa-miR-1 hsa-mir-1-2 18 15685193
hsa-miR-1 hsa-mir-1-1 20 15685193
hsa-miR-124 hsa-mir-124-1 8 15685193
hsa-miR-124 hsa-mir-124-2 8 15685193
hsa-miR-124 hsa-mir-124-3 20 15685193
hsa-miR-133a hsa-mir-133a-1 18 21304530
hsa-miR-133a hsa-mir-133a-2 20 21304530
hsa-miR-139-5p hsa-mir-139 11 21304530
hsa-miR-204 hsa-mir-204 9 21304530
hsa-miR-370 hsa-mir-370 14 21304530
hsa-miR-373 hsa-mir-373 19 15685193
hsa-miR-373* hsa-mir-373 19 15685193
ID in Tarbase Data Type Support Type miRNA Gene Direct Support Publication
211 Unknown MicroArray miR-1 TAGLN2 n_a 15685193
1203 Unknown pSILAC miR-1 TAGLN2 down >75% 18668040
Ensembl Protein Type Differentially expressed in Pathology or Event Mis Regulation Gene Expression Tumour Involvement
ENSG00000158710 "cardiac and skeletal muscles, cardiogenesis" n_a n_a n_a n_a
ENSG00000158710 n_a n_a n_a n_a n_a
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
1788 mRNA chr1 156702678 156708345 247 mRNA TAGLN2 chr1 156700975 156708357Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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