AutismKB 2.0

Annotation Detail for ULK1


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Basic Information Top
Gene Symbol:ULK1 ( ATG1,ATG1A,FLJ38455,FLJ46475,UNC51,Unc51.1 )
Gene Full Name: unc-51-like kinase 1 (C. elegans)
Band: 12q24.33
Quick LinksEntrez ID:8408; OMIM: 603168; Uniprot ID:ULK1_HUMAN; ENSEMBL ID: ENSG00000177169; HGNC ID: 12558
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
450Phosphoserine.
456Phosphothreonine.
469Phosphoserine.
477Phosphoserine.
479Phosphoserine.
556Phosphoserine.
623Phosphoserine.
625Phosphothreonine (By similarity).
638Phosphoserine.
717Phosphothreonine.
758Phosphoserine.
Location(AA) Modifications Resource
556Phosphoserine.Swiss-Prot 53.0
556PhosphoserinePhospho.ELM 6.0
625Phosphothreonine (By similarity).Swiss-Prot 53.0
638Phosphoserine.Swiss-Prot 53.0
Location(AA) Modification Resource
89Phosphotyrosine(SRC)HMM predict
89Phosphotyrosine(Syk)HMM predict
187Phosphotyrosine(INSR)HMM predict
187Phosphotyrosine(Abl)HMM predict
187Phosphotyrosine(SRC)HMM predict
195Phosphoserine(ATM)HMM predict
225Phosphoserine(CDC2)HMM predict
236N-linkedHMM predict
287Phosphoserine(CDC2)HMM predict
300Phosphoserine(IKK)HMM predict
300Phosphoserine(CK2)HMM predict
307Phosphoserine(CK1)HMM predict
307O-linkedHMM predict
308Phosphoserine(CK1)HMM predict
314Phosphoserine(MAPK)HMM predict
317Phosphoserine(IKK)HMM predict
330Phosphoserine(CDC2)HMM predict
350Phosphoserine(IKK)HMM predict
351Phosphoserine(IKK)HMM predict
385Phosphoserine(ATM)HMM predict
401Phosphothreonine(CDK)HMM predict
401O-linkedHMM predict
401Phosphothreonine(MAPK)HMM predict
403Phosphoserine(CDC2)HMM predict
403O-linkedHMM predict
403Phosphoserine(CDK)HMM predict
403Phosphoserine(IKK)HMM predict
403Phosphoserine(ATM)HMM predict
405O-linkedHMM predict
410Phosphoserine(CK1)HMM predict
411Phosphoserine(CDC2)HMM predict
413Phosphoserine(CDC2)HMM predict
417MethylarginineHMM predict
422O-linkedHMM predict
441Phosphotyrosine(EGFR)HMM predict
456Phosphothreonine(MAPK)HMM predict
469Phosphoserine(CDC2)HMM predict
477Phosphoserine(MAPK)HMM predict
477Phosphoserine(CDC2)HMM predict
477O-linkedHMM predict
479O-linkedHMM predict
479Phosphoserine(ATM)HMM predict
479PhosphoserineHMM predict
502Phosphotyrosine(Jak)HMM predict
503Phosphothreonine(CDK)HMM predict
503Phosphothreonine(MAPK)HMM predict
505Phosphoserine(CDC2)HMM predict
518O-linkedHMM predict
520Phosphothreonine(CDC2)HMM predict
520Phosphothreonine(CDK)HMM predict
522Phosphoserine(CDK)HMM predict
522Phosphoserine(CDC2)HMM predict
529MethylarginineHMM predict
533Phosphoserine(CDC2)HMM predict
538Phosphoserine(CK2)HMM predict
539O-linkedHMM predict
588O-linkedHMM predict
605Phosphoserine(CDC2)HMM predict
605Phosphoserine(CDK)HMM predict
623Phosphoserine(CDC2)HMM predict
623Phosphoserine(CDK)HMM predict
636Phosphothreonine(CDK)HMM predict
636Phosphothreonine(MAPK)HMM predict
654Phosphothreonine(CDK)HMM predict
654Phosphothreonine(CDC2)HMM predict
658N-linkedHMM predict
716Phosphoserine(IKK)HMM predict
746O-linkedHMM predict
746O-linkedHMM predict
747O-linkedHMM predict
747O-linkedHMM predict
748Phosphoserine(CDC2)HMM predict
750O-linkedHMM predict
758O-linkedHMM predict
761O-linkedHMM predict
761O-linkedHMM predict
761Phosphoserine(ATM)HMM predict
761Phosphoserine(IKK)HMM predict
763O-linkedHMM predict
764Phosphothreonine(CDC2)HMM predict
764Phosphothreonine(CDK)HMM predict
764O-linkedHMM predict
770MethylarginineHMM predict
771Phosphothreonine(PKC)HMM predict
775O-linkedHMM predict
781O-linkedHMM predict
1022Phosphoserine(ATM)HMM predict
1029N-linkedHMM predict
1042SerineHMM predict
1042Phosphoserine(PKG)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_003565
  • Location:chr12 130945231-130973648
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 130932853 130933077 224 12267
CTCF G2GSE9613 130933820 130935070 1250 10787
FOXA1 MCF7GSE15244 130934453 130935070 617 10470
GATA3 MCF7GSE15244 130934418 130935070 652 10488
H3ac HepG2E 130934685 130935070 385 10354
NRSF pAbJurkat 130933785 130934047 262 11316
PHF8 HeLaGSE20725 130944731 130945707 976 13
RARA MCF7GSE15244 130932853 130933077 224 12267
RARA MCF7GSE15244 130934453 130935070 617 10470
RARG MCF7GSE15244 130934453 130935070 617 10470
TFAP2C MCF7GSE21234 130927537 130928232 695 17347
TFAP2C MCF7GSE21234 130933618 130934744 1126 11051
USF1 HepG2E 130934756 130935070 314 10319
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T30-glioblastomaGSE21026 130962824 130963627 803 0
CTCF G2GSE9613 130944902 130947829 2927 0
CTCF G2GSE9613 130948430 130948763 333 0
CTCF G2GSE9613 130950924 130951364 440 0
CTCF G2GSE9613 130953375 130954614 1239 0
CTCF G2GSE9613 130956110 130956567 457 0
CTCF G2GSE9613 130957823 130960500 2677 0
CTCF G2GSE9613 130961334 130962119 785 0
CTCF G2GSE9613 130963596 130963801 205 0
CTCF G2GSE9613 130964233 130965216 983 0
CTCF G2GSE9613 130966284 130967773 1489 0
CTCF G2GSE9613 130968060 130969190 1130 0
CTCF G2GSE9613 130969578 130970645 1067 0
CTCF G2GSE9613 130971028 130971853 825 0
CTCF G2GSE9613 130972277 130973014 737 0
FOXA1 DLD1GSE12801 130946473 130947005 532 0
FoxA1 MCF7MACSdata 130946475 130946744 269 0
NRSF pAbJurkat 130945510 130946020 510 0
NRSF pAbJurkat 130959646 130960565 919 0
NRSF pAbJurkat 130963482 130963801 319 0
NRSF pAbJurkat 130965615 130967773 2158 0
NRSF pAbJurkat 130971923 130972316 393 0
P300 T30-glioblastomaGSE21026 130962867 130963526 659 0
PHF8 293TGSE20725 130944845 130945757 912 0
PHF8 HeLaGSE20725 130945855 130947213 1358 0
PHF8 Hs68minusFBSGSE20725 130945023 130945752 729 0
PHF8 Hs68plusFBSGSE20725 130945027 130945607 580 0
Rb GrowingGSE19898 130947088 130947287 199 0
Rb GrowingGSE19898 130947384 130947537 153 0
Rb QuiescentGSE19898 130946895 130947355 460 0
Rb SenescentGSE19898 130946773 130947395 622 0
Rb shRbQuiescentGSE19898 130946793 130947153 360 0
Rb shRbSenescenceGSE19898 130946839 130947300 461 0
TFAP2C MCF7GSE21234 130952407 130952918 511 0
TFAP2C MCF7GSE21234 130962816 130963505 689 0
hScc1 BcellGSE12603 130958441 130959504 1063 0
hScc1 BcellGSE12603 130959796 130960536 740 0
hScc1 BcellGSE12603 130967172 130967548 376 0
hScc1 BcellGSE12603 130970383 130970783 400 0
hScc1 BcellGSE12603 130971853 130972422 569 0
hScc1 CdLSGSE12603 130951890 130952105 215 0
hScc1 G2GSE9613 130958126 130959144 1018 0
hScc1 G2GSE9613 130959610 130960225 615 0
p130 QuiescentGSE19898 130946763 130947358 595 0
p130 SenescentGSE19898 130947047 130947700 653 0
p130 shRbQuiescentGSE19898 130946268 130946687 419 0
p130 shRbSenescentGSE19898 130946679 130947093 414 0
p130 shRbSenescentGSE19898 130947136 130947388 252 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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