AutismKB 2.0

Annotation Detail for ASCC2


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:ASCC2 ( ASC1p100 )
Gene Full Name: activating signal cointegrator 1 complex subunit 2
Band: 22q12.2
Quick LinksEntrez ID:84164; OMIM: NA; Uniprot ID:ASCC2_HUMAN; ENSEMBL ID: ENSG00000100325; HGNC ID: 24103
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
713Phosphoserine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
23Phosphothreonine(PKC)HMM predict
142Phosphoserine(MAPK)HMM predict
192Phosphoserine(CK2)HMM predict
220N-linkedHMM predict
222Phosphothreonine(CDK)HMM predict
222Phosphothreonine(CDC2)HMM predict
378Phosphoserine(CK1)HMM predict
412Phosphothreonine(PKA)HMM predict
438Phosphoserine(IKK)HMM predict
438Phosphoserine(ATM)HMM predict
441Phosphoserine(CK2)HMM predict
447Phosphoserine(CK1)HMM predict
447Phosphoserine(CK2)HMM predict
515Phosphoserine(ATM)HMM predict
530Phosphothreonine(MAPK)HMM predict
530Phosphothreonine(CDK)HMM predict
534Phosphothreonine(PKC)HMM predict
564Phosphothreonine(PKC)HMM predict
590Phosphotyrosine(SRC)HMM predict
611Phosphotyrosine(Syk)HMM predict
612SulfotyrosineHMM predict
616SulfotyrosineHMM predict
616Phosphotyrosine(Syk)HMM predict
616Phosphotyrosine(INSR)HMM predict
620Phosphotyrosine(Syk)HMM predict
620Phosphotyrosine(INSR)HMM predict
632Phosphoserine(CK1)HMM predict
632Phosphoserine(CK2)HMM predict
632PhosphoserineHMM predict
713O-linkedHMM predict
713Phosphoserine(CDC2)HMM predict
715MethylarginineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_032204
  • Location:chr22 28514602-28564253
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T30-glioblastomaGSE21026 28568447 28569345 898 4643
Gata2 K562GSE18868 28566517 28566960 443 2485
Nanog hESGSE18292 28568387 28568698 311 4289
p130 SenescentGSE19898 28564492 28564678 186 332
p130 shRbQuiescentGSE19898 28564269 28564681 412 222
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3ac HepG2E 28506733 28507360 627 7556
H3ac HepG2E 28508068 28509045 977 6046
Rb GrowingGSE19898 28509308 28509482 174 5208
TFAP2C MCF7GSE21234 28506947 28507475 528 7392
TFAP2C MCF7GSE21234 28513112 28513982 870 1056
hScc1 BcellGSE12603 28508220 28508763 543 6111
p130 SenescentGSE19898 28506682 28507221 539 7651
p130 SenescentGSE19898 28507235 28507568 333 7201
p130 shRbQuiescentGSE19898 28506764 28507364 600 7539
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T30-glioblastomaGSE21026 28524779 28525830 1051 0
CBP T30-glioblastomaGSE21026 28547229 28547724 495 0
ER MCF7GSE19013 28524588 28525676 1088 0
FOXA1 MCF7GSE15244 28524435 28525350 915 0
FOXA1 MCF7GSE15244 28539169 28539863 694 0
Fos K562GSE19551 28539462 28539927 465 0
FoxA1 MCF7MACSdata 28537406 28537638 232 0
Gata2 K562GSE18868 28524862 28525612 750 0
Gata2 K562GSE18868 28547225 28547829 604 0
H3K4me3 colorectalcancer 28563441 28563883 442 0
H3ac HepG2E 28563441 28563883 442 0
P300 T30-glioblastomaGSE21026 28524275 28526116 1841 0
PHF8 HeLaGSE20725 28563661 28564701 1040 0
RARA MCF7GSE15244 28524661 28525754 1093 0
RARA MCF7GSE15244 28539307 28540717 1410 0
RARG MCF7GSE15244 28524435 28525754 1319 0
RARG MCF7GSE15244 28539270 28540284 1014 0
Rb SenescentGSE19898 28525190 28525580 390 0
TFAP2C MCF7GSE21234 28521524 28522128 604 0
TFAP2C MCF7GSE21234 28524615 28525728 1113 0
TFAP2C MCF7GSE21234 28537414 28537800 386 0
TFAP2C MCF7GSE21234 28539499 28540398 899 0
TFAP2C MCF7GSE21234 28547158 28547858 700 0
hScc1 BcellGSE12603 28514901 28515426 525 0
p130 SenescentGSE19898 28525145 28525564 419 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018