AutismKB 2.0

Annotation Detail for STX7


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Basic Information Top
Gene Symbol:STX7 ( - )
Gene Full Name: syntaxin 7
Band: 6q23.2
Quick LinksEntrez ID:8417; OMIM: 603217; Uniprot ID:STX7_HUMAN; ENSEMBL ID: ENSG00000079950; HGNC ID: 11442
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
2N-acetylserine.
3Phosphotyrosine.
45Phosphoserine (By similarity).
79Phosphothreonine.
125Phosphoserine (By similarity).
126Phosphoserine (By similarity).
129Phosphoserine.
205Phosphoserine (By similarity).
Location(AA) Modifications Resource
2N-acetylserine.Swiss-Prot 53.0
79Phosphothreonine (By similarity).Swiss-Prot 53.0
125Phosphoserine (By similarity).Swiss-Prot 53.0
126Phosphoserine (By similarity).Swiss-Prot 53.0
129Phosphoserine (By similarity).Swiss-Prot 53.0
Location(AA) Modification Resource
69Phosphotyrosine(Jak)HMM predict
75Phosphoserine(IKK)HMM predict
79PhosphothreonineHMM predict
79Phosphothreonine(CDK)HMM predict
79Phosphothreonine(MAPK)HMM predict
125O-linkedHMM predict
131Phosphoserine(CK2)HMM predict
131Phosphoserine(IKK)HMM predict
137Phosphoserine(CK1)HMM predict
161Phosphothreonine(CK2)HMM predict
173Phosphoserine(CK1)HMM predict
174Phosphoserine(CK1)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_003569
  • Location:chr6 132822848-132875858
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Fos K562GSE19551 132875683 132876342 659 154
H3ac HepG2E 132876553 132877031 478 934
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
hScc1 BcellGSE12603 132819625 132820056 431 3008
hScc1 CdLSGSE12603 132819334 132820280 946 3042
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 132847089 132847314 225 0
CTCF CD4SISSRdata 132847089 132847314 225 0
CTCF G2GSE9613 132847204 132847554 350 0
H3ac HepG2E 132873835 132874199 364 0
NRSF JurkatSISSRdata 132875611 132875803 192 0
Oct1 H2O2-HelaGSE14283 132863262 132863290 28 0
Oct1 HelaGSE14283 132849315 132849345 30 0
Oct1 HelaGSE14283 132863262 132863290 28 0
Rb GrowingGSE19898 132827642 132827904 262 0
USF1 HepG2E 132873609 132874266 657 0
hScc1 BcellGSE12603 132847095 132847554 459 0
hScc1 CdLSGSE12603 132846820 132847554 734 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-let-7b hsa-let-7b 22 18668040
hsa-let-7b* hsa-let-7b 22 18668040
hsa-miR-1 hsa-mir-1-2 18 18668040
hsa-miR-1 hsa-mir-1-1 20 18668040
hsa-miR-155 hsa-mir-155 21 18668040
hsa-miR-155* hsa-mir-155 21 18668040
hsa-miR-16 hsa-mir-16-1 13 18668040
hsa-miR-16 hsa-mir-16-2 3 18668040
hsa-miR-30a hsa-mir-30a 6 18668040
hsa-miR-30a* hsa-mir-30a 6 18668040
hsa-miR-30b hsa-mir-30b 8 18668040
hsa-miR-30b* hsa-mir-30b 8 18668040
hsa-miR-30c hsa-mir-30c-2 6 18668040
hsa-miR-30c hsa-mir-30c-1 1 18668040
hsa-miR-30c-1* hsa-mir-30c-1 1 18668040
hsa-miR-30c-2* hsa-mir-30c-2 6 18668040
hsa-miR-30d hsa-mir-30d 8 18668040
hsa-miR-30d* hsa-mir-30d 8 18668040
hsa-miR-30e hsa-mir-30e 1 18668040
hsa-miR-30e* hsa-mir-30e 1 18668040
ID in Tarbase Data Type Support Type miRNA Gene Direct Support Publication
1285 Unknown pSILAC miR-30 STX7 down 50-25% 18668040
Ensembl Protein Type Differentially expressed in Pathology or Event Mis Regulation Gene Expression Tumour Involvement
ENSG00000079950 n_a n_a n_a "epithelium, lymphoblast, lymphocyte, muscle cell" "benign tumour, malignant tumour, carcinoma, leukaemia, sarcoma"
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
23179 mRNA chr6 132836352 132836897 545 mRNA STX7 chr6 132822847 132875859 Non-exonic Bidirectional (NOB) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018