AutismKB 2.0

Annotation Detail for DDI2


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Basic Information Top
Gene Symbol:DDI2 ( MGC14844,RP4-680D5.5 )
Gene Full Name: DNA-damage inducible 1 homolog 2 (S. cerevisiae)
Band: 1p36.21
Quick LinksEntrez ID:84301; OMIM: NA; Uniprot ID:DDI2_HUMAN; ENSEMBL ID: ENSG00000197312; HGNC ID: 24578
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
106Phosphoserine.
120Phosphoserine (By similarity).
121Phosphoserine (By similarity).
128Phosphoserine.
194Phosphoserine.
Location(AA) Modifications Resource
120Phosphoserine (By similarity).Swiss-Prot 53.0
121Phosphoserine (By similarity).Swiss-Prot 53.0
128Phosphoserine (By similarity).Swiss-Prot 53.0
194Phosphoserine.Swiss-Prot 53.0
Location(AA) Modification Resource
45Phosphoserine(PKG)HMM predict
104O-linkedHMM predict
106Phosphoserine(CDK)HMM predict
106Phosphoserine(CDC2)HMM predict
108MethylarginineHMM predict
115O-linkedHMM predict
120Phosphoserine(CK1)HMM predict
121Phosphoserine(CDC2)HMM predict
121Phosphoserine(ATM)HMM predict
128Phosphoserine(CDC2)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_032341
  • Location:chr1 15816656-15859334
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 15816523 15816786 263 2
ETS1 JurkatGSE17954 15815663 15817309 1646 171
Fos K562GSE19551 15802378 15803092 714 13922
FoxA1 MCF7MACSdata 15800664 15800810 146 15920
H3ac HepG2E 15814605 15814770 165 1969
HIF1 NormHepG2 15802323 15803009 686 13991
KLF4 hESGSE17917 15816210 15816677 467 213
PHF8 293TGSE20725 15816060 15817176 1116 39
RARA MCF7GSE15244 15802108 15803344 1236 13931
Rb SenescentGSE19898 15816270 15816834 564 105
Rb shRbQuiescentGSE19898 15816501 15816656 155 78
Rb shRbSenescenceGSE19898 15816513 15816713 200 44
USF1 HepG2E 15801590 15801757 167 14983
USF1 HepG2E 15802108 15804372 2264 13417
USF1 HepG2E 15805036 15805749 713 11264
USF2 HepG2E 15801590 15801757 167 14983
USF2 HepG2E 15802108 15804372 2264 13417
USF2 HepG2E 15805036 15805749 713 11264
hScc1 BcellGSE12603 15802468 15802687 219 14079
hScc1 BcellGSE12603 15803620 15803952 332 12871
p130 QuiescentGSE19898 15816160 15816318 158 418
p130 QuiescentGSE19898 15816517 15816664 147 66
p130 SenescentGSE19898 15802167 15802835 668 14156
p130 shRbQuiescentGSE19898 15802160 15802710 550 14222
p130 shRbSenescentGSE19898 15802464 15803110 646 13870
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER E2-MCF7GSE14664 15839022 15839062 40 0
H3ac HepG2E 15817024 15818166 1142 0
H3ac HepG2E 15818990 15819437 447 0
H3ac HepG2E 15820096 15820456 360 0
Oct1 HelaGSE14283 15835938 15835977 39 0
Oct1 HelaGSE14283 15839020 15839053 33 0
PHF8 HeLaGSE20725 15816050 15817295 1245 0
RARA MCF7GSE15244 15817261 15818166 905 0
TAF HelaGSE8489 15817225 15818166 941 0
TAF k562GSE8489 15817103 15818166 1063 0
TAF k562GSE8489 15818845 15819995 1150 0
hScc1 BcellGSE12603 15816523 15816881 358 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018